Dr. Zainab Lafi

Assistant Professor

Major: Pharmaceutical sciences /Molecular pharmacology

Department: Pharmaceutics and Pharmaceutical Technology Department

Faculty: Faculty of Pharmacy


Email:

z.lafi@ammanu.edu.jo

Extention: 2288

Profiles:



COURSES TAUGHT

  • Pharmaceutical Biotecnology
  • Drug delivery systems
  • Pharmacy Ethics and Legislation
  • Practical Pharmaceutical Lab
  • Practical drug dispensing and pharmaceutics
  • Pharmaceutical Organic Lab
  • Instrumental Lab
  • Advanced pharmaceutical biotechnology
  • graduation project
  • bio-pharmaceutics and and pharmacokinatics
  • Pharmaceutical Marketing

ACADEMIC RANKS

Rank University Country Date
Associate Professor AL-Ahliyya Amman university Jordan 2024
Assistant Professor Middle East University-Amman Jordan 2020
Lecturer Jordan university Jordan 2014

QUALIFICATION

Degree Institute Specialization Country Date
ماجستير Jordan University pharmacology الأردن February / 2014
دكتوراة Jordan University Pharmaceutical sciences الأردن June / 2020
بكالوريوس Jordan university of science and technology Pharmy الأردن June / 1991

WORK EXPERIENCE

Job Title Institute Time Period
Faculty member/Associate Professor Al- Ahliyya Amman University November / 2024 - January / Present
Faculty member/ Assistant Professor Al- Ahliyya Amman University September / 2022 - November / 2024
Faculty member / Assistant Professor Middle East University -Amman Jordan September / 2020 - September / 2022
Part time Lecturer Jordan University January / 2013 - January / 2018
Pharmacist Community Pharmacy January / 1991 - January / 2009

RESEARCH INTERESTS

  • Nanotechnology
  • Anticancer drugs
  • Drug interactions
  • Bio pharmaceutical formulation

RESEARCHES AND PUBLICATIONS

  • Zainab Lafi, Tha’er Ata & Sherine Asha (2025) CRISPR in clinical diagnostics: bridging the gap between research and practice Bioanalysis, 1(2025):1–10
  • HUSSEIN S. JANABI, ZAINAB LAFI,SINA MATALQAH (2025) HPLC METHOD DEVELOPMENT AND VALIDATION FOR METFORMIN AND PHENYL BUTYRIC ACID AND IN VITRO EVALUATION OF THEIR PEGYLATED LIPOSOMAL FORMULATION AGAINST COLORECTAL CANCER International Journal of Applied Pharmaceutics (Int J App Pharm), May-Jun 2025
  • S. Matalqah, Z Lafi, A Y. Al-Kabariti (2025) A Recent Review of PLGA-PEG Hybrid Nanoparticles for Anticancer and AntiInflammatory Applications Jordan Journal of Pharmaceutical Sciences, 18 No. 1 (2025)
  • Maisrh Ali Alrubaye, Zainab Lafi, Maha N. Abu Hajleh, Tamer M.M. Abuamara, Afnan Mehdawi (2025) Co-encapsulation of coumarin and Q10 into solid lipid nanoparticles for wound healing Journal of Drug Delivery Science and Technology, 105, (2025), 106645
  • Walhan Alshaer, Zainab Lafi, Hamdi Nsairat, Baidaa AlQuaissi, Dana A Alqudah, Hadil Zureigat, Islam Hamad (2025) Remote Co-Loading of Doxorubicin and Hydralazine into PEGylated Liposomes: In Vitro Anti-Proliferative Effect Against Breast Cancer Molecules , 2025, 30(7), 1549;
  • Abu Saleem, E., Lafi, Z., Shalan, N., Alshaer, W., & Hamadneh (2025) Formation and evaluation of doxorubicin and cromoglycate metal–organic framework for anti-cancer activity Nanomedicine, 1(2025) 1-13
  • Matalqah, S., Lafi, Z., Mhaidat, Q., Asha, N., & Yousef Asha, S (2025) ‘Applications of machine learning in liposomal formulation and development’ Pharmaceutical Development and Technology, (2025) 1-11
  • Sina Matalqah, Zainab Lafi, Sara. Y. Asha (2024) Hyaluronic Acid in Nanopharmaceuticals: An Overview Curr. Issues Mol. Biol., 46(9)10444-10461
  • AliFahdawi, Naeem Shalan, Zainab Lafi*, Omar Markab (2024) Analytical Approaches for Assessing Curcumin and Nicotinamide Co-Encapsulated in Liposomal Formulation: UV Spectrophotometry and HPLC Validation Jordan Journal of Pharmaceutical Sciences, 17(3)468 -480
  • Ali Allateef,, Shalan N., Lafi Z. (2024) Anticancer activity of liposomal formulation co-encapsulated with coumarin and phenyl butyric acid Journal of Applied Pharmaceutical Science, 2024;14(11):208–215.
  • Zainab Lafi, Sina Matalqah, Ebaa Abu-Saleem, Nisreen Asha, Hala Mhaidat, Sherine Asha, Lara Al-Nashash & Hussein S. Janabi (2024) Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment Medical Oncology, 42(1) 26, (2025)
  • Ahmed Munef, Zainab Lafi, Naeem Shalan (2024) Investigating anti-cancer activity of dual-loaded liposomes with thymoquinone and vitamin C Therapeutic Delivery, 15 (4):267-278
  • Zainab Lafi Lobna Gharaibeh, Hamdi Nsairat, Nisreen Asha & Walhan Alshaer (2023) Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring Bioanalysis, 17/0141
  • Hamdi Nsairat Walhan Alshaer , Zainab Lafi , Somaya Ahmad, Alaa Al-Sanabrah & Mohamed El-Tanani (2023) Development and validation of reversed-phase-HPLC method for simultaneous quantification of fulvestrant and disulfiram in liposomes Bioanalysis, 17/0137
  • Hamdi Nsairat, Zainab Lafi, Mazen Al-Sulaibi, Lobna Gharaibeh, Walhan Alshaer. (2023) Impact of Nanotechnology on the Oral Delivery of Phyto-bioactive Compounds. Food Chemistry , 224/136438
  • Zainab Lafi, Walhan Alshaer, Ma’mon M. Hatmal , Malek A. Zihlif , Nisreen Y. Asha , Hiba Abdelnabi, Abdullah Awidi. (2023) Echinomycin: A journey of challenges. Jordan Journal of Pharmaceutical sciences., 16, No. 3, 2023
  • Hafsa Al Azzawia, Walhan Alshaer, Ezaldeen Esawia, Zainab Lafi, Duaa Abuarqoub, Rand Zaza, Manar Zraikat, Abdel kader Battah, Abdalla Awidia., (2023) Multifunctional nanoparticles recruiting hyaluronic acid ligand and polyplexes containing low molecular weight protamine and ATP-Sensitive DNA motif for doxorubicin delivery. Journal of Drug Delivery Science and Technology, 69/ 1031650
  • Zainab Lafi , Walhan AlshaerID *, Lobna Gharaibeh , Dana A. Alqudah Baidaa AlQuaissi , Banan Bashaireh , Abed Alqader Ibrahim (2023) Synergistic combination of doxorubicin with hydralazine, and disulfiram against MCF-7 breast cancer cell line PLOS ONE , 8 (9 e0291981
  • Ezaldeen Esawi, Hamdi Nsairat, Ismail Sami Mahmoud, Zainab Lafi, Abdulfattah Al-Kadash, Bayan Abu Al-Ragheb, Said I Ismail, Walhan Alhaer (2023) Clinical use and future perspective of aptamers Woodhead Publishing, 481-520
  • Zainab Lafi, Nour Aboalhaija, Fatma Afifi. (2022) Ethnopharmacological importance of local flora in the traditional medicine of Jordan: A mini review. Jordan Journal of Pharmaceutical sciences., 15 (1), 132-144.
  • Walhan Alshaer 1,†, Hamdi Nsairat 2,†, Zainab Lafi 2, Omar M. Hourani 3, Abdulfattah Al‐Kadash 1, Ezaldeen Esawi 1 and Alaaldin M. Alkilany (2022) Quality by Design Approach in Liposomal Formulations: Robust Product Development Molecules, 8(1):10, 2022
  • Hammad HM, Imraish A, Al-Hussaini M, Zihlif M, Harb AA, Abu Thiab TM, Zainab Lafi, Nassar ZD, Afifi FU. (2021) Ethanol Extract of Achillea fragrantissima Enhances Angiogenesis through Stimulation of VEGF Production. J Pharmacogn Phytochem Sep., (21)/ 2035-2042(8)
  • Zainab Lafi, Walhan Alshaer, Ma’mon M. Hatmal, Malek Zihlif, Dana A. Alqudah, Hamdi Nsairat, Hanan Azzam, Talal Aburjai, Yasser Bustanji, Abdalla Awidi; (2021) Aptamer-functionalized pH-sensitive liposomes for selective delivery of echinomycin into cancer cells. RSC advances, , (47) 11, 29164-29177
  • L Zainab, T Hiba, A Hanan (2020) An updated assessment on anticancer activity of screened medicinal plants in Jordan: Mini review. Zainab Lafi, Tarik Hiba and Azzam Hanan Journal of Pharmacognosy and Phytochemistry, 9 (5), 55-58
  • Walhan Alshaer‡ ORCID logo*a, Manar Zraikat‡ b, Amer Amer c, Hamdi Nsairat d, Zainab Lafi c, Dana A. Alqudah a, Enas Al Qadi b, Tasneem Alsheleh b, Fadwa Odeh d, Arwa Alkaraki ab, Malek Zihlif b, Yasser Bustanji ce, Elias Fattal ORCID logof and Abdalla Awidi (2019) Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma. RSC advances, 9, 30976-30988.
  • ZM Lafi, YM Irshaid, M El-Khateeb, KM Ajlouni, D Hyassat (2017) Association of rs7041 and rs4588 polymorphisms of the vitamin D binding protein and the rs10741657 polymorphism of CYP2R1 with vitamin D status among Jordanian patients Humboldt Kolleg "Jordanian Life Sciences for Sustainable, 19 (11), 629-636
  • ZM Lafi, YM Irshaid, M El-Khateeb, KM Ajlouni, D Hyassat (2015) Association of rs7041 and rs4588 Polymorphisms of the Vitamin D Binding Protein and the rs10741657 Polymorphism of CYP2R1 with Vitamin D Status Among Jordanian Patients. Genetic testing and molecular biomarkers, 19 (11), 629-636

Published Books:

  • 20 - Clinical use and future perspective of aptamers (2023) "Aptamers Engineered Nanocarriers for Cancer Therapy Elsevier

THESIS SUPERVISION

Title Location Date
Synthesis of Bimetallic Nanoparticles Loaded with Olive Mill Waste: Characterization and Evaluation of their Antibacterial and Cytotoxicity Effect Al-Ahliyya Amman University 2025
Formulation, Characterization, and Biological Evaluation of Curcumin and Metformin Niosomal Preparations Al-Ahliyya Amman University 2025
Evaluation of the effect of combination therapy of Asprin and atrovastatin nanoparticles in the treatment of colorectal cancer Al-Ahliyya Amman University 2024
Investigation of anticancer activity of curcumin and nicotinamide as liposomal formulation Al-Ahliyya Amman University 2024
Formation and Evaluation of Doxorubicin and Cromoglycate Metal Organic Framework for Anti-Cancer Activity Al-Ahliyya Amman University 2024
Co-encapsulation of coumarin and Q10 into Solid lipid nanoparticles for wound healing Al-Ahliyya Amman University 2024
Investigating the Therapeutic Potential of Co-loaded Liposomes of Cisplatin and Etoricoxib for anti-breast cancer Al-Ahliyya Amman University 2024
“Formulation and evaluation of metformin and Phenyl butyric acid liposomes for anticancer activity” Al-Ahliyya Amman University 2024
Curcumin and Nicotinamide liposomal formulation for Skin Infection Al-Ahliyya Amman University 2023
Anticancer activity of liposomal formulation co-encapsulated with coumarin and phenylbutyric acid. Al-Ahliyya Amman University 2023
Formulation and characterization of Liposomes Co-encapsulated with Vitamin C and Thymoquinone and its Anti-cancer Activity. Al-Ahliyya Amman University 2023

Al-Ahliyya Amman University

Email: Public@ammanu.edu.jo

 

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