• Biochemistry Lab
• Biology Lab
• Molecular Lab
• Genetics Lab
• Animal Physiology Lab
• Practical Molecular Diagnostic
• General Biology Lab
• Molecular Biology

• Genetic Polymorphisms & SNPs Research
• Pharmacogenomics Research
• Molecular Targeting of Cancer

• Amer Imraish 1, Walhan Alshaer 2, Tuqa Abu-Thiab 1, Fatima Enaya 1, Hamzeh J Al-Ameer 3, Afnan Al-Hunaiti 4, Mohammad Abumurad 5, Malek Zihlif 5 (2025) siRNA Knocking Down in HepG2 Cells Identifies PFKFB4 and HNF4α as Key Genes Important for Cancer Cell Survival Current gene therapy, Volume 25, Issue 5 , 2025,747-760
• Hamzeh J. Al-Ameer, Malek Zihlif, Ahmed Maslat, Wajdy J. Al-Awaida, Amani Marwan Ayyash, Amer Imraish, Nidal Al-Qinna, Tareq Al-Omari, Talal Al-Qaisi, Walid Al-Zyoud, Bayan T. Alzubi, Ali M. Atoom, Isam A. Fattash, Shubhankar Ambike, Khang Wen Goh & Yulia Sh. Gushchina (2024) Targeting the proliferation of glioblastoma cells and enhancement of doxorubicin and temozolomide cytotoxicity through inhibition of PFKFB4 and HMOX1 genes with siRNAs scientific reports, 15,1,2025,27861
• Suhair Sunoqrot, Mohammad Abu Shalhoob, Yazun Jarrar, Alaa M Hammad, Hamzeh J Al-Ameer, Wajdy Al-Awaida (2024) Nanoencapsulated Curcumin Mitigates Liver Injury and Drug-Metabolizing Enzymes Induction in Diclofenac-Treated Mice ACS Omega, Issue 4, Volume 9, 2024
• Omar M. Atrooz, Makarem Al-Awaida, Wajdy Al-Awaida, Hamzeh J. Al-Ameer, Hamdi Uysal (2024) Evaluating the Antioxidant Capacity, Phenolic Contents, and Anticancer Potential of Caralluma europaea Extracts Advancements in Life Sciences, Volume 11, Issue 4, 2024, Pages 862 - 870
• Asma' Al‑Zabin, Tuqa Abu Thiab, Malek Zihlif, Afnan Al‑Hunaiti, Hamzeh J Al‑Ameer, Wajdy Al‑Awaida, Amer Imraish (2024) Anti‐angiogenic and cytotoxic evaluation of green‐synthesized Fe2ZnO4 nanoparticles against MCF‐7 cell line Biomedical Reports, 20,3, 2024 ,1-9
• Amer Imraish, Malek Zihlif, Tuqa Abu-Thiab, Wajdy Al-Awaida, Hamzeh J Al-Ameer, Basha'er Abu-Irmaileh, Afnan Al-Hunaiti (2024) ANTI-INFLAMMATORY AND ANTIOXIDANT EFFECTS OF ROSMARINIC ACID TRIMETALLIC (Cu0.5Zn0.5Fe2O4) NANOPARTICLES Chemistry & Biodiversity, -
• Afnan Al-Hunaiti, Malek Zihlif, Tuqa Abu Thiab, Wajdy Al-Awaida, Hamzeh J Al-Ameer, Amer Imraish (2024) Magnetic nanoparticle-based combination therapy: Synthesis and in vitro proof of concept of CrFe2O4- rosmarinic acid nanoparticles for anti-inflammatory and antioxidant therapy Plos one, 8,19,2024,e0297716
• Mahmoud A Al-Qudah, Faten M Abu Orabi, Ghalya M Sheikhekraim, Jamil N Lahham, Hala I Al-Jaber, Abdulrahman G Alhamzani, Abbas I Alakhras, Tareq T Bataineh, Hamzeh J Al-Ameer, Sultan T Abu-Orabi (2024) Cytotoxicity, Antioxidant Activity and Phytochemical Screening of Four Euphorbia Species from Jordan Tropical Journal of Natural Product Research, 2023; 7(12):5540-5547
• Abd Al-Rahman Al-Shudiefat, Hadeel Alturk, Hamzeh J Al-Ameer, Malek Zihlif, Maha Alenazy (2023) Olive Leaf Extract of Olea europaea Reduces Blood Glucose Level through Inhibition of AS160 in Diabetic Rats Applied Sciences, 10, 13, 5939
• Wajdy Al-Awaida, Hamzeh J Al-Ameer, Ahmad Sharab, Rand T Akasheh (2023) Modulation of wheatgrass (Triticum aestivum Linn) toxicity against breast cancer cell lines by simulated microgravity Current Research in Toxicology, Volume 5, 2023, 100127
• Nour Al-Kazimi, Yazun Jarrar, Ghasaq Abdul-Wahab, Ahmad R. Alsayed, Abdalla Madani, Dina Abulebdah, Rami Salem Musleh, Qais Jarrar, Hamzeh J Al-Ameer, Wajdy Al-Awaida & Eman Abdullah (2023) Effects of intermittent fasting on the histology and mRNA expression of major drug-metabolizing cyp450s in the liver of diabetic mice Libyan Journal of Medicine, 18,1,2023, 2270188
• Wajdy Al-Awaida 1,* , Khang Wen Goh 2 , Hamzeh J. Al-Ameer 3 , Yulia Sh. Gushchina 4, Vladimir I. Torshin 5, Alexandr E. Severin 5, Omar Al Bawareed 5, Besan Srour 1, Jude Al Farraj 1 and Islam Hamad 6 (2023) Assessing the Protective Role of Epigallocatechin Gallate (EGCG) against Water-Pipe Smoke-Induced Toxicity: A Comparative Study on Gene Expression and Histopathology Molecules, 2023, 28(22)
• Abdulqader F Abed, Yazun Bashir Jarrar, Hamzeh J Al-Ameer, Wajdy Al-Awaida, Su-Jun Lee (2022) The protective effect of metformin against oxandrolone-induced infertility in male rats Current Pharmaceutical Design, 4, 28, 324-330
• Malek Zihlif, Suhad Otoum, Mohammad Al Shhab, Zaid Almadani, Monther Momani, Hussam Alhawari, Yazun Jarrar, Hamzeh Al-ameer, Amer Imraish (2022) No association between LDL receptor and CETP genetic variants and atorvastatin response in Jordanian hyperlipidemic patients Drug Metabolism and Personalized Therapy, 4, 37, 369-374
• Wajdy J Al-Awaida, Hamzeh J Al-Ameer, Ahmad Sharab, Ghizal Fatima, Najah R Hadi (2022) THE ATP-BINDING CASSETTE TRANSPORTER A1 GENE POLYMORPHISMS AND TYPE 2 DIABETES MELLITUS Era's Journal of Medical Research, 1, 9, 45-51
• Wajdy Al‐Awaida, Hamzeh J Al‐Ameer, Hadeel Al‐Turk, Omar Al Bawareed, Raida Khalil, Akram Al Deek, Ghizal Fatima, Amer Imraish, Moh’d Mohanad Al‐Dabet, Muhanad W Akash (2022) Psychological effects of quarantine on Syrian refugees, compared to the Jordanian populations International Migration, 1, 60, 219-227
• Musa I El-Barghouthi, Ayman S Hasan, Wajdy Al-Awaida, Hamzeh J Al-Ameer, Jatinder Kaur, Kaita J Hayashibara, Jeremy Fleming, Jessica Waknin, Shigeo Hayashibara, Muna Slewa, Samer M Hamzeh, Khaled Bodoor, Joshua Daniel McLoud, Frank Wuest, Baker Jawabrah Al Hourani (2022) Novel therapeutic heterocycles as selective cyclooxygenase-2 inhibitors and anti-cancer agents: Synthesis, in vitro bioassay screenings, and molecular docking studies Journal of Molecular Structure, 1263, 133141
• Ali A. Ahmed1, Asia Ali Hamza2, Ayat J. Nashwan 3, Yulia Gushchina4,Muha-nad W. Akash5, Basem F Dababneh6, Hamzeh J. Al-Ameer7, Amani Marwan Ayyash8, Rand H. Nsour9, Ahmad Sharab7,Omar Al bawareed10, Najah R. Hadi11, Vladimir Troshin12,Agamurad A. Orazmuradov13,Severin A.E.14,Ba-kaeva Z.V15,Wajdy J. Al-Awaida*7 (2022) The Psychological Impact Of The COVID-19 Pandemic On Syrian Refugee Students, Compared To The Jordanian Students In Jordanian Universities Journal of Positive School Psychology, 8, 6, 3371-3389
• Abeer Jabra Shnoudeh, Lana Qadumii, Malek Zihlif, Hamzeh J Al-Ameer, Ruba Anwar Salou, Abdulmutalleb Yousef Jaber, Islam Hamad (2022) Green synthesis of gold, iron and selenium nanoparticles using phytoconstituents: Preliminary evaluation of antioxidant and biocompatibility potential Molecules, 4, 27, 1334
• Fatima Khirfan, Yazun Jarrar, Tariq Al-Qirim, Khang Wen Goh, Qais Jarrar, Chrismawan Ardianto, Mohammad Awad, Hamzeh J Al-Ameer, Wajdy Al-Awaida, Said Moshawih, Long Chiau Ming (2022) Analgesics induce alterations in the expression of SARS-CoV-2 entry and arachidonic-acid-metabolizing genes in the mouse lungs Pharmaceuticals, 6, 15, 696
• Ma’mon M Hatmal, Mohammad AI Al-Hatamleh, Amin N Olaimat, Rohimah Mohamud, Mirna Fawaz, Elham T Kateeb, Omar K Alkhairy, Reema Tayyem, Mohamed Lounis, Marwan Al-Raeei, Rasheed K Dana, Hamzeh J Al-Ameer, Mutasem O Taha, Khalid M Bindayna (2022) Reported Adverse Effects and Attitudes among Arab Populations Following COVID-19 Vaccination: A Large-Scale Multinational Study Implementing Machine Learning Tools in Predicting Post-Vaccination Adverse Effects Based on Predisposing Factors Vaccines, 3, 10, 366
• Baker F Al-Mubideen, Ala-Aldeen A Al-Serhan, Justin Z Amarin, Arwa Al-Dweikat, Ra’ad Z Al-Muhaisen, Yusra Abu Shreikh, Haya H Suradi, Hamzeh J Al-Ameer, Malek A Zihlif (2021) Ononis natrix L. Lowers the Blood Glucose Concentration in Wistar Rats with Streptozotocin-induced Diabetes Mellitus Endocrine, Metabolic & Immune Disorders-Drug Targets , 5, 21, 854-858
• Raida Khalil, Wajdy J Al-Awaida, Hamzeh J Al-Ameer, Yazun Jarrar, Amer Imraish, Omar Al Bawareed, Rand Qawadri, Farah Al Madhoon, Loiy Obeidat (2021) Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 genotypes in Jordanian patients with fibromyalgia syndrome Endocrine, Metabolic and Immune Disorders - Drug Targets, 10, 21, 1920-1928
• Wajdy J. Al-Awaida, Baker Jawabrah Al Hourani, Samer Swedan, Refat Nimer, Foad Alzoughool, Hamzeh J. Al-Ameer, Sara E. Al Tamam, Raghad Alashqar, Omar Al Bawareed, Yulia Gushchina, Mohamed Samy Abousenna, Amani Marwan Ayyash, Ahmad Sharab, Sulaiman M. Alnaimat, Amer Imraish, Muhanad W. Akash, Najah R. Hadi (2021) Correlates of SARS-CoV-2 Variants on Deaths, Case Incidence and Case Fatality Ratio among the Continents for the Period of 1 December 2020 to 15 March 2021 Genes, 7, 12, 1061
• Wajdy Al Awaida, Ali A Ahmed, Asia Ali Hamza, Khalid I Amber, Hamzeh J Al-Ameer, Yazun Jarrar, Ghizal Fatima, Ahmed O Maslat, Yulia Gushchina, Najah R Hadi (2021) Association of KDR rs1870377 genotype with clopidogrel resistance in patients with post percutaneous coronary intervention Heliyon, 2, 7
• Sima Zein, Wajdy J Al-Awaida, Olga M Yuldasheva, Andrey S Khakimov, Sergey M Chibisov, Yulia Gushchina, Omar A Al Bawareed, Vladimir I Torshin, Еlena В Yakunin, Hamzeh J Al-Ameer, Irina V Podoprigora (2021) Influence of geographic conditions on body length of male newborns in Kyrgyzstan International Journal of Biometeorology, 65, 2053-2057
• Amer Imraish, Tuqa Abu Thiab, Wajdy Al‐Awaida, Hamzeh J Al‐Ameer, Yasser Bustanji, Hana Hammad, Mays Alsharif, Afnan Al‐Hunaiti (2021) In vitro anti-inflammatory and antioxidant activities of ZnFe2O4 and CrFe2O4 nanoparticles synthesized using Boswellia carteri resin Journal of Food Biochemistry, 6, 45, e13730
• H Rouibah, W Kebsa, M Lahouel, M Zihlif, M Ahram, B Aburmaileh, MA AL SHHAB, HJ Al-Ameer, E Mustafa (2021) ALGERIAN PROPOLIS: BETWEEN PROTECTION OF NORMAL CELLS AND POTENTIALISATION OF THE ANTICANCER EFFECTS OF DOXORUBICIN AGAINST BREAST CANCER CELLS VIA P-GLYCOPROTEIN INHIBITION AND CELL CYCLE ARREST IN THE S PHASE Journal of Physiology & Pharmacology, 2, 72
• Ma’mon M Hatmal, Walhan Alshaer, Ismail S Mahmoud, Mohammad AI Al-Hatamleh, Hamzeh J Al-Ameer, Omar Abuyaman, Malek Zihlif, Rohimah Mohamud, Mais Darras, Mohammad Al Shhab, Rand Abu-Raideh, Hilweh Ismail, Ali Al-Hamadi, Ali Abdelhay (2021) Investigating the association of CD36 gene polymorphisms (rs1761667 and rs1527483) with T2DM and dyslipidemia: Statistical analysis, machine learning based prediction, and meta-analysis PLoS ONE, 10, 16, e0257857
• Ammar Sobiahe, Eman Hijazi, Hamzeh J Al-Ameer, Yazan Almasri, Yazun Jarrar, Malek Zihlif, Maha Shomaf, Baeth Al-Rawashdeh (2020) Arg399Gln XRCC1 polymorphism and risk of squamous cell carcinoma of the head and neck in Jordanian patients Asian Pacific journal of cancer prevention: APJCP, 3, 21, 2020, 663
• Ma’mon M Hatmal, Salim M Abderrahman, Wajeha Nimer, Zaynab Al-Eisawi, Hamzeh J Al-Ameer, Mohammad AI Al-Hatamleh, Rohimah Mohamud, Walhan Alshaer (2020) Artificial Neural Networks Model for Predicting Type 2 Diabetes Mellitus Based on VDR Gene FokI Polymorphism, Lipid Profile and Demographic Data Biology, 8, 9,, 2020, 222
• WAJDY J Al-Awaida, HAMZEH J Al-Ameer, MOHAMED SAMY Abousenna, REFAT Nimer, HAYAT O Al-Asasfeh, SEVERIN ALEXANDER Evgenievich, YAKUNINA ELENA BORISOVNA, BAKAEVA ZARINA VAGICAINE, OMAR AL BAWAREED, BAKER JAWABRAH AL-HOURANI, NAJAH R HADI (2020) SARS-Cov-2 Genomic Variations Among Isolates from Jordanian Patients International Journal of Pharmaceutical Research (IJPR) , 12, 3917-3925
• Wajdy J Al-Awaida, Ahmad S Sharab, Hamzeh J Al-Ameer, Nabil Y Ayoub (2020) Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats npj Microgravity, 1, 6, 2020, 6
• Wajdy J Al‐Awaida, Malek A Zihlif, Hamzeh J Al‐Ameer, Ahmad Sharab, Muhanad Akash, Zaid A Aburubaiha, Isam A Fattash, Amer Imraish, Khedhir H Ali (2019) The effect of green tea consumption on the expression of antioxidant‐and inflammation‐related genes induced by nicotine Journal of food biochemistry, 7, 43, 2019, e12874
• Ma’mon M Hatmal, Nada N Issa, Walhan Alshaer, Hamzeh J Al-Ameer, Omar Abuyaman, Reema Tayyem, Nawal S Hijjawi (2019) Association of Breastfeeding Duration with Susceptibility to Allergy, Influenza, and Methylation Status of TLR1 Gene Medicina, 9, 55, 2019, 535
• Ismail Sami Mahmoud, Ayat Homsi, Hamzeh J Al-Ameer, Jihad Alzyoud, Mais Darras, Mohammad Al Shhab, Malek Zihlif, M Hatmal Ma’mon, Walhan Alshaer (2019) Screening the RFX6-DNA binding domain for potential genetic variants in patients with type 2 diabetes World Journal of Diabetes, 3, 10, 2019, 181
• Hassiba Rouibah, Wided Kebsa, Mesbah Lahouel, Malek Zihlif, Mamoun Ahram, Bachaer Aburmeleih, Ebtihal Mustafa, Hamzeh J Al-Ameer (2018) Algerian Propolis Potentiates Doxorubicin Mediated Anticancer Effect Against Human Pancreatic PANC-1 Cancer Cell Line through Cell Cycle Arrest, Apoptosis Induction and P-Glycoprotein Inhibition Anti-Cancer Agents in Medicinal Chemistry, 3, 18, 2018, 375-387
• Wided Kebsa, Mesbah Lahouel, Hassiba Rouibah, Malek Zihlif, Mamoun Ahram, Bashaer Abu-Irmaileh, Ebtihal Mustafa, Hamzeh J Al-Ameer, Mohammad Al Shhab (2018) Reversing Multidrug Resistance in Chemo-resistant Human Lung Adenocarcinoma (A549/DOX) Cells by Algerian Propolis Through Direct Inhibiting the P-gp Efflux-pump, G0/G1 Cell Cycle Arrest and Apoptosis Induction Anti-Cancer Agents in Medicinal Chemistry, 9, 18, 2018, 1330-1337
• Zina A Habib-Martin, Hana M Hammad, Fatma U Afifi, Malek Zihlif, Hamzeh J Al-Ameer, Mohanad M Saleh, Ismail F Abaza, Zeyad D Nassar (2017) In vitro and in vivo evaluation of the antiangiogenic activities of Trigonella foenum-graecum extracts Asian Pacific Journal of Tropical Biomedicine, 8, 7, 2017, 732-738
• Sawsan Abuhamdah, A Shatarat, M Al-Essa, H Al-Ameer, S Al-Olimat, P Chazot (2017) Spasmolytic and antimicrobial activities of crude extract of Bongardia Chrysogonum L. tubers. International journal of pharmacology., 1, 14, 2017, 52-60

Published Books:

• (2023) Title: Targeting The Proliferation of U87 Glioblastoma Cells Through siRNA Inhibition of PFKFB4 and HO-1 Genes Yarmouk University