Al-Ahliyya Amman University
Dr. Reem Issa
Associate Professor
Major: Phytochemistry
Departemnt: Pharmaceutical Sciences Department
Faculty: Faculty of Pharmacy
Email:
Extention: 2146
Profiles:
COURSES TAUGHT
- PHYTOCHEMISTRY
- PHYTOTHERAPY
ACADEMIC RANKS
| Rank | University | Country | Date |
|---|---|---|---|
| Associate Professor | Applied since private university | Jordan | 2017 |
QUALIFICATION
| Degree | Institute | Specialization | Country | Date |
|---|---|---|---|---|
| Phd | University of Warwick | phytochemistry | المملكة المتحدة | July / 2010 |
| Masters Degree | University of Jordan | Pharmacy | الأردن | August / 2005 |
| Bachelors Degree | Applied Science University | Pharmacy | الأردن | February / 2003 |
WORK EXPERIENCE
| Job Title | Institute | Time Period |
|---|---|---|
| Academic staff | Al-Ahliya Amman University | September / 2020 - January / Present |
| FACULTY MEMEBER | Yarmouk University | September / 2018 - September / 2020 |
| FACULTY MEMBER | Applied Science University | September / 2010 - September / 2018 |
RESEARCH INTERESTS
- ordanian Medicinal plants Extraction , Phytochemical analysis and standardization: an approach for new pharmaceutical formulations My m ain interest is in natural products chemistry, specifically secondary plants metabolites, and the ir qualitative and quantitative measurements in different biological masses. In addition, I am interested in the evaluation of plant extracts efficiency in terms of: The inhibit ion of enzymatic reactions in invitro studies, for different pharmaceutical applications , including their antioxidant activity , antimicrobial, anticancer and antityrosinase effect. The evaluat ion of the hypoglycemic and hypolipidaemic potential, for different plant extracts, on normal and streptozotocin induced mild and severely diabetic rats. The evaluat ion of the potential effect of different plant extracts, on folate absorption and leptin activity on female rats. The evaluation of t wo different methods for extraction; including microwave- integrated soxhlet extraction and the conventional s oxhlet extraction methods for the comparative study of their pharmacological effects, using different models and relating these effects with their metabolites profile. Qualitative and quantitative analysis of secondary plant metabolites using HPLC -MS / MS / UV analysis. Linking the pharmacological effects obtained from the studied plant extracts with their phytochemical profile. V Optimize the extraction protocol used to obtain special extracts requir ed for certain pharmaceutical applications. The incorporation of standardized plant extracts that processes specific biological or pharmacological activity in a novel pharmaceutical formulation.
- Herbal Medicine in Jordan: Ethnic Drug Surveys and Verba l Laboratory Studies Also, I am interested in conducting research in the area of herbal remedies that have been used by Jordanian herbalists and pharmacists in ethnomedicine, ethno- botany and phytotherapeutic, with the aim of clinical evaluation and valid ation of these preparations. Users believe and practices are also explored and used to understand their knowledge and behaviors towards herbal medicine . In this regards, validated questioners and face -to-face interviews are the main tools used. In addition, literature review using respected open access data bases are also used for validation of the efficient and safe use of these remedies. Such findings would be used to pave the way for making new recommendations in order to customize special strategies , which can be implemented in the country in aim to resolve critical issues influencing the use of herbal remedies.
RESEARCHES AND PUBLICATIONS
- Al-Bayati, M., Issa, R., Abu-Samak, M., Alnsour, L., Awwad, S. (2023) Phytochemical analysis and evaluation of anti-hyperlipidaemic effect for ethanolic leaf extract of Equisetum ramosissimum L.: in vivo study on rats’ models PHARMACIA, 70(3), pp. 557-568
- Shady Awwad1 , Ahmed Abu-Zaiton2 , Reem Issa3 , Rana Said3 , Ahmad Sundookah4, Maha Habash5, Beisan Mohammad6, Mahmoud Abu-Samak7 (2023) The effect of excessive coffee consumption, in relation to diterpenes levels of mediumroasted coffee, on non-high-density lipoprotein cholesterol level in healthy men PHARMACIA, 70(1): 49–5
- Al-Halaseh, L.K., Abu Hajleh, M.N., Al-Samydai, A., Majali, S., Issa, R., Said, R., Ahmed, M.A.M. (2022) EVALUATION OF RHEUM PALMATUM RHIZOMES AVAILABLE IN JORDANIAN MARKETS AND INVESTIGATION OF ITS POTENTIAL USE AS HAIR DYE COSMETICS Bulletin of Pharmaceutical Sciences. Assiut, 45(2), pp. 605-613
- Azal Hussein Najm Ubaydee MSc, Reem Issa PhD, Maha N. Abu Hajleh PhD, Bayan Y. Ghanim MSc, Faisal Al-Akayleh PhD, Nidal A. Qinna PhD (2022) The effect of Medicago sativa extract and light on skin hypopigmentation disorders in C57/BL6 mice journal cosmetic dermatology, 2022;00:1–11
- Al-Halaseh, L.K., Sweiss, M.A., Issa, R.A., (...), Abu Hajleh, M.N., Al-Samydai, A.M. (2022) Nephroprotective Activity of Green Microalgae, Chlorella sorokiniana isolated from Jordanian Water Journal of Pure and Applied Microbiology, 16(4), pp. 2775-2782
- Lilian Alnsour ,Reem Issa , Shady Awwad ,Dima Albals , andIdrees Al-Momani (2022) Quantification of Total Phenols and Antioxidants in Coffee Samples of Different Origins and Evaluation of the Effect of Degree of Roasting on Their Levels molecules, 2022, 27(5), 1591
- Ali Al-Samydai 1,*ORCID,Moath Al Qaraleh 1ORCID,Walhan Alshaer 2ORCID,Lidia K. Al-Halaseh 3ORCID,Reem Issa 1ORCID,Fatima Alshaikh 1,Aseel Abu-Rumman 1ORCID,Hayat Al-Ali 4 andEmad A. S. Al-Dujaili 5 (2022) Preparation, Characterization, Wound Healing, and Cytotoxicity Assay of PEGylated Nanophytosomes Loaded with 6-Gingerol Nutrients, 2022, 14(23), 5170
- Abdulhakeem Hasan1 , Reem Issa1 , Lidia Al-Halaseh2 , Manal A. Abbas3 , Nariman Al-Jawabri2 , Rawan Al-Suhaimat2 (2022) Investigation of the nephroprotective activity of Moringa peregrina leaves aqueous extract in mice PHARMACIA, 69(4): 1095–1102
- Sara M. Daboul , Mohammad Abusamak , Beisan A. Mohammad , Ahmad R. Alsayed , Maha Habash , Ibrahim Mosleh , Sami Al-Shakhshir , Reem Issa , Mahmoud Abu-Samak (2022) The Effect of Omega-3 Supplements on The Serum Levels Of ACE/ACE2 Ratio As A Potential Key in Cardiovascular Disease: A Randomized Clinical Trial in Participants with Vitamin D Deficiency PHARMACY PRACTICE, Vol. 21 No. 1 (2023): Jan-Mar
- Awwad, S., Issa, R., Alnsour, L., Albals, D., Al-Momani, I. (2021) Quantification of caffeine and chlorogenic acid in green and roasted coffee samples using hplc-dad and evaluation of the effect of degree of roasting on their levels molecules, 26(24),7502
- Dima Albals, Idrees F Al-Momani, Reem Issa, Alaa Yehya (2021) Multi-element determination of essential and toxic metals in green and roasted coffee beans: A comparative study among different origins using ICP-MS Science Progress, 104, (2)
- Issa, R., Albals, D., Yehya, A., Shriedh, F. (2021) Assessment of lifestyle, herbs, dietary and pharmacological preventive measures used among the public in Jordan to boost immunity during COVID-19 pandemic Tropical Journal of Pharmaceutical Research, 20(9), pp. 1969-1974
- Mohammad Kattuoa, Reem Issa, Soha Beitawi (2020) Commonly used herbal remedies for the treatment of Primary Dysmenorrhea and Heavy Menstrual Bleeding by herbalists in Amman, Jordan: A cross- sectional survey Jordan Journal of Pharmaceutical Sciences, xxxxx
- Aysha Al Khalaf, Reem Issa , Areen Khattabi (2020) Extraction of vitamin C, phenols and carotenoids from Capsicum annuum and their use as antioxidant, antimicrobial and coloring agents for pharmaceutical applications. Pakistan Journal of Biological Sciences, 12: 524- 534.
- Alaa Yehya, Dima Albals , Reem Issa, Aida Fawadleh (2020) Retrospective Assessment of Acute Poisoning Incidents by Non -Pharmaceutical Agents in Jordan: Pharmacy One TM Poison Call Centers' Data, 2014 to 2018 –Part I. Pharmacology Research & Perspectives, 8 (2), e00582 .
- Alaa Yehya, Dima Albals , Reem Issa *, Aida Fawadleh (2020) Retrospective Assessment of Acute Poisoning Incidents by Pharmaceutical Agents in Jordan: Pharmacy One TM Poison Call Cent ers' Data, 2014 to 2018 - Part II. Pharmacology Research & Perspectives, 8 (2), e00583 .
- Abed Savaya, N.S., Issa, R.A., Talib, W.H. (2020) In vitro evaluation of the antioxidant, anti-Propioni bacterium acne and antityrosinase effects of Equisetum ramosissimum (Jordanian horsetail) Tropical Journal of Pharmaceutical Research, 19(10), pp. 2147-2152
- Reem Issa , Iman Bashiti , Lubna Abu- Khadejieh and RulaTayeh (2019) Pharmacistsʼ and patientsʼ knowledge and perceptions regarding the use of herbal treatments for memory impairment: A cross -sectional study from Jordan. Asian J. Sci. Res., 12: 524-534.
- (2019) Herbal Remedies used in Ethnomedicine in Jordan 1st FIP Regional Conference for the Eastern Mediterranean,
- ssa, R., Khattabi, A., Alkarem, T. A., & Altameemi, O. (2019) he Use of Antidiabetic Herbal Remedies by Jordanian Herbalist: A Comparison f Folkloric Practice vs. Evidence - Based Pharmacology Jordan Journal of Pharmaceutical Sciences, 12(3).
- Halees, R. Y., Talib , W. H., & Issa, R. A . (2019) Varthemia iphionoides and Pelargonium graveolens Extracts as a Treatment of Breast Cancer Implanted in Diabetic Mice. Pharmacognosy Magazine, 15(65), 698.
- Reem Issa (2018) Use of herbal remedies, conventional medicine, diet and exercise for weight loss: Case of university students in Jordan. Pak. J. Nutr., 17:76-88.
- (2018) An Update on Herbal Remedies used in Ethnomedicine, Ethnobotany and Phytotherapeutic by Jordanian Patients, Herbalists and Pharmacists Speaker at the 9th International Conference of the Royal Medical Services . ( Oral presentation) : An Update on Herbal Remedies used in Ethnomedicine, Ethnobotany and Phytotherapeutic by Jordanian Patients, Herbalists and Pharmacists, 2018.,
CONFERENCES AND WORKSHOPS
| Conference Title | Type of Participation | Location | Date |
|---|---|---|---|
| 1st FIP Regional Conference for the Eastern Mediterranean | Paper/Poster | Jordan | April / 2019 |
| Speaker at the 9th International Conference of the Royal Medical Services . ( Oral presentation) : An Update on Herbal Remedies used in Ethnomedicine, Ethnobotany and Phytotherapeutic by Jordanian Patients, Herbalists and Pharmacists, 2018. | Paper/Poster AND Participate in the organization of Conference | Jordan | October / 2018 |
THESIS SUPERVISION
| Title | Location | Date |
|---|---|---|
| The protective effect of Moringa peregrina leaves extracts against infertility in animal male model | Al-Ahliya Amman University | 2023 |
| In vitro studies on fortified carotenoids-rich collagen from the mucus of the snail Helix aspersa as a component of cosmetics and pharmaceutical products | Al-Ahliya Amman University | 2023 |
| Evaluation of cytotoxicity and antibacterial activity of green synthesized silver nanoparticles using Hedera helix extract | Al-Ahliya Amman University | 2023 |
| The effect of Hedera helix leaves extract on fertility parameters in animal male model | Al-Ahliya Amman University | 2023 |
| The Nephron Protective Effect of Equisetum ramosissimum L. Extract in Streptozotocin-induced Diabetic Rats | Amman Aahliya h university | 2022 |
| The effect of Medicago sativa extract and light on induced skin hypopigmentation disorders using mice model | Amman Aahliya h university | 2022 |
| Phytochemical analysis of Moringa peregrina leaves extract and evaluation of potential Nephroprotective effect in animal model | Amman Aahliya h university | 2022 |
| ENCAPSULATION OF GINGEROLS INTO NANOLIPOSOMES: EVALUATION OF IN-VITRO ANTI-INFLAMMATORY AND ANTI-CANCER ACTIVITY | Amman Aahliya h university | 2022 |
| Phytochemical analysis and in vitro studies on Sisymbrium officinale different extracts | Amman Aahliya h university | 2022 |
| Phytochemical analysis and evaluation of anti-hyperlipidaemic effect for ethanolic leaf extract of Equisetum ramosissimum L.: in vivo study on rats’ models | Amman Aahliya university | 2022 |
| A Retrospective Study of the Potential Adverse Effects of Commonly Used Herbal Medicine and Dietary Supplements on Patients Undergoing Surgical Operations Under General Anesthesia | Amman Aahliya university | 2022 |
| Co -supervisor of the student Ahmed Iyad Ali Al -Rawi was discussed on 17/12/2017 entitled: Title: Anticanc `er and immunomodulatory activities of Jordanian Citrullus colocynthis | Applied science university | 2018 |
| Principal supervisor of the student N oor Sabah Abdul Safaya discussed on 17/1/2018 entitled: Title: Investigating the total phenolic content, anti- aging, anti -acne and anti - hyperpigmentational effects of Jordanian horsetail ( Equisetum ramosissimum ): An in vitro study. | Applied science university | 2018 |
| Principal supervisor of the student Aisha alkhalaf discussed on 30/8/2018 entitled: Title: Extraction and characterization of total phenolic and antioxidant compounds from Jordanian Capsicum annum species and their use as colouring agent. | Applied science university | 2018 |
| Co -supervisor of student Rana Yousef Al-Hallis was discussed on 11/1/2017 entitled: Title: Screening anti- diabetic plants as a treatment of breast cancer implanted in diabetic mice | Applied science university | 2017 |
AWARDS AND SCHOLARSHIP
| Title | Location | Date |
|---|---|---|
| NA | 2020 |
