Dr. Israa Al-Ani

Associate Professor

Major: Pharmaceutics/ Biopharmaceutics and Pharmacokinetics

Departemnt: Pharmaceutics and Pharmaceutical Technology Department

Faculty: Faculty of Pharmacy


Email:

ialani@ammanu.edu.jo

Extention: 2397

Profiles:



COURSES TAUGHT

  • Industrial Pharmacy
  • Biopharmaceutics and Pharmacokinetics
  • Biopharmaceutics and Pharmacokinetics practical
  • Advanced pharmaceutical technology
  • Drug delivery systems
  • Drug delivery systems
  • Physical pharmacy
  • Physical pharmacy practical
  • General chemistry practical
  • Practical pharmaceutics

ACADEMIC RANKS

Rank University Country Date
Associate Professor Al-Ahliyya Amman University Amman 2019
Associate Professor Al-Ahliyya Amman University Amman 2019
Associate Professor Al-Ahliyya Amman University Amman 2019
Assistant Professor University of Baghdad Iraq 2007

QUALIFICATION

Degree Institute Specialization Country Date
Phd College of Pharmacy-University of Baghdad Pharmaceutics July / 2007
Masters Degree College of Pharmacyl University of Baghdad May / 2000
Bachelors Degree College of Pharmacy-University of Baghdad Pharmacy June / 1992

WORK EXPERIENCE

Job Title Institute Time Period
Faculty member Al-Ahliyya Amman University October / 2019 - March / Present
Assisstant prof Faculty of Pharmacy , Al-Ahliyya Amman University February / 2010 - October / 2019
Teacher and Ph.D student College of Pharmacy, University of Baghdad September / 2004 - June / 2007
Teacher and researcher College of Pharmacy, University of Baghdad June / 2000 - September / 2004
M.SC student College of Pharmacy, University of Baghdad September / 1998 - May / 2000
Teaching assistant College of Pharmacy, University of Badhdad, July / 1992 - October / 1998

RESEARCH INTERESTS

  • Biopharmaceutica and pharmacokinetics
  • Pharmaceutical Technology
  • Drug Delivery Systems

RESEARCHES AND PUBLICATIONS

  • Zainab N. Salman, Israa Al-Ani, Khaldun M. Al Azzam,, Bashar J. M. Majeed, Hassan H. Abdallah and El-Sayed Negim (2023) Enhancement of apixaban's solubility and dissolution rate by inclusion complex (β-cyclodextrin and hydroxypropyl β-cyclodextrin) and computational calculation of their inclusion complexes ADMET and DMPK, 0(0):1-18
  • Mustafa Ayesh, Israa Al-Ani *, Naeem Shalan , Fatima Tawfiq , Sina Matalqah , Enas Daoud 6, Randa Atwan 7, Bayan Abdul Majeed , Rolla Alshalabi , Wael Abu Dayyih (2023) Formulation and Evaluation of Metformin-Vildagliptin Combination as Oral Dispersible Tablets Al-Balqa Journal for health and Applied sciences, 2(1): 23-33
  • Rawan Karaki , Mohammad Hailat , Israa Al-Ani , Zainab Zakaraya , Lina N.Tamimi 4, Sina M. Matalqah 3,5, Rehan Al-Kasasbeh ,Wael Abu Dayyih , Mohammed Hamad (2023) Effects of Liquorice Juice on the Pharmacokinetics of Esomeprazole Journal of Population Therapeutics & Clinical Pharmacology, 30(3):e673–e681
  • Rawan Karaki 1, Wael Abu Dayyih 1 , Mohammad M. Hailat 2, Abdulwahab M. Al-Badri3, Mohammed Hamad4, Lina N. Tamimi 5, Rehan Al-Kasasbeh1, Israa Al-Ani6, Zainab Zakaraya6, Sina M. Matalq6, Mohammad Abu Assab 5 (2023) Evaluation of Naproxen and Esomeprazole in Bulk and Pharmaceutical Tablets Dosage Form by RP-Chromatography Journal of Population Therapeutics & Clinical Pharmacology, Vol 30(5):e75–e84;2023
  • Zaid Majeed Ismaeel, Israa Al-Ani, Maha N. Abu Hajleh, Emad Al-Dujaili (2023) Formulation and evaluation of retinyl palmitate and vitamin E nanoemulsion for skin care Pharmacia, 70 (3) : 475–483
  • Ali Jaber , Israa Al-Ani ,*, Mohammad Hailat , Enas Daoud , Anmar Abu-Rumman , Zainab Zakaraya , Bashar J.M. Majeed , Osaid Al Meanazel , Wael Abu Dayyih (2022) Esomeprazole and apixaban pharmacokinetic interactions in healthy rats Heliyon, 8 (2022) e11015
  • Yaseen T. Khalaf *, Yasir Q. Almajidi1,**, Naeem M. Shalan*, Israa H. Alani* and Wael A. Abu Dayyih (2022) Preparation and Evaluation of Oroslippery Tablets Contain Irbesartan and Hydrochlorothiazide Combination Iraqi Journal of Pharmaceutical Sciences, 31 (2): 91-100
  • Yaseen T. Khalaf *, Yasir Q. Almajidi1,**, Naeem M. Shalan*, Israa H. Alani* and Wael A. Abu Dayyih (2022) Preparation and Evaluation of Oroslippery Tablets Contain Irbesartan and Hydrochlorothiazide Combination Iraqi Journal of Pharmaceutical Sciences, Vol.31( 2 ) 2022
  • Mohammad Hailat 1 , Zainab Zakaraya 2, Israa Al-Ani 2, Osaid Al Meanazel 3, Ramadan Al-Shdefat 4, Md. Khalid Anwer 5 , Mohamed J. Saadh 6 and Wael Abu Dayyih (2022) Pharmacokinetics and Bioequivalence of Two Empagliflozin, with Evaluation in Healthy Jordanian Subjects under Fasting and Fed Conditions Pharmaceuticals, 2022, 15, 193.
  • Mustafa Muhammed, Israa Al-Ani1*, Enas Daoud, Nawfal Numan , Ashok Shakya, and Wael Abu Dayyih (2022) Formulation and in-vitro evaluation of metformin-tadalafil combination as oro-dispersible tablets Sapporo Medical Journal, Volume 56, Issue 08, August 2022
  • Mohammad Hailat , Israa Al-Ani , Zainab Zakareia , Ramadan Al-Shdefat , Osaid Al-Meanazel , Md. Khalid Anwer 5,* , Mohammed Hamad , Walid Abu Rayyan , Riad Awad and Wael Abu Dayyih (2022) Development and Validation ofHPLC-DADMethod for the Determination of Favipiravir and Studying the Impact of Vitamin C on the Pharmacokinetics of COVID-19 AntiviralDrug Favipiravir Separation, 2022, 9, 303
  • ISRAA AL ANI2, , RAMADAN I. AL-SHDEFAT, ZAINAB ZAKAREIA, SARAH ALI HAMID and ASHOK K. SHAKYA (2021) Development and Validation of a Stability-Indicating HPLC Method for Empagliflozin and Linagliptin in Tablet Dosage Form Asian Journal of Chemistry, Vol. 33, No. 2 (2021), 484-488
  • WAEL ABU DAYYIH1, , ISRAA AL ANI2, , RAMADAN I. AL-SHDEFAT3, ZAINAB ZAKAREIA1, SARAH ALI HAMID4 and ASHOK K. SHAKYA (2021) Development and Validation of a Stability-Indicating HPLC Method for Empagliflozin and Linagliptin in Tablet Dosage Form Asian Journal of Chemistry, Vol. 33, No. 2 (2021)
  • Muhana, F., Al-Ani, I., Al-Akayleh, F., Marzouqa, D., Khalili, F., Al-Khatib, H., Mutti, H., & Shalan, N. (2021) Synthesis and characterization of mesoporous silica and its application as drug delivery system for glimepiride. Die Pharmazie, 76(7), 2021;300–307.
  • MAHER FARES, ISRAA AL-ANI, MOHAMMAD HAILAT, ANAS KHALEEL, PHIL COLLIER1, ASMAA AL-ANI, WAEL ABU DAYYIH (2021) Evaluation the Impact of Grapefruit Juice on Sitagliptin Pharmacokinetics in Healthy Rats International Journal of Pharmaceutical Research, Apr - Jun 2021 , Vol 13 , Issue 2
  • Israa Al-Ani 1, Mohammed Hamad 2, Ramadan Al-Shdefat 3, Kenza Mansoor 4, Felicia Gligor 5 and Wael Abu Dayyih (2021) DEVELOPMENT AND VALIDATION OF A STABILITY INDICATING RP-HPLC METHOD OF APIXABAN IN COMMERCIAL DOSAGE FORM International Journal of Pharmaceutical Sciences and Research, 2021; Vol. 12(1): 241-251
  • Mohammad Hailat 1 , Israa Al-Ani 2, Mohammed Hamad 3 , Zainab Zakareia 4 and Wael Abu Dayyih (2021) Development and Validation of a Method for Quantification of Favipiravir as COVID-19 Management in Spiked Human Plasma Molecules, 2021, 26, 3789.
  • Al-Shdefat, R., Al-Ani, I., Tamimi, L., Awad, R., Rayyan, W. A., & Dayyih, W. A. (2021) Development and Validation of a Stability-Indicating HPLC-DAD Method for the Determination of Canagliflozin and Metformin Simultaneously in Combination Dosage Form. Pharmaceutical Chemistry Journal. , Vol. 55, No. 4, July, 2021
  • Abdulrahman Al-Bazzaz, Kahtan A-Dahir, Abdulsalam Almashhadani and Israa Al-Ani (2020) Estimation of Fasting Serum Levels of Glucose, Zinc, Copper, Zinc /Copper Ratio and Their Relation to the Measured Lipid Profile in Autistic Patients and Non-Autistic Controls in Jordan Biomedical & Pharmacology Journal, Vol. 13(1), p. 481-488
  • Israa Al-Ani , Fatima Tawfiq , Zainab Zakarya , Wael Abu Dayyih (2020) Some Fractal Aspects in Biopharmaceutics and Pharmacokinetics Review International Journal of Pharmaceutical Research & Allied Sciences, 2020, 9(4):55-63
  • Israa Al-Ani 1, Fatima Tawfiq 1, Zainab Zakarya 2, Wael Abu Dayyih (2020) Some Fractal Aspects in Biopharmaceutics and Pharmacokinetics Review International Journal of Pharmaceutical Research & Allied Sciences, 9(4):55-63
  • Abeer Mohammad Kharshid, Syed Azhar Syed Sulaiman, Israa H Al-Ani, Riad M Awad, Mohammad M Hailat, Wael Abu Dayyih (2020) Knowledge, Attitudes, and Perceptions of Healthcare Professionals towards Early Referral and Using Statins in Non-dialysis CKD Patients Systematic Reviews in Pharmacy, 11(7)475-481
  • Israa H. Al-Ani#, Ashok K. Shakya, Samira F. Hassan (2019) Design, Optimization, and Evaluation of Combined Dosage form of Amoxicillin and Nonsteroidal Anti-inflammatory Agent for Pediatric use using DoE Asian Journal of Pharmaceutics, 13 (2) | 125
  • (2019) Msc student research, ASU-Pharmacy Forth National Conference (Recent trends in postgraduate studies),
  • Alhuda ALANBAKI *, Israa ALANI**, Eyad Mallah*, Zainab ZAKAREIA*, Tawfiq ARAFAT*, Wael ABU DAYYIH (2019) The effect of Pomegranate and Licorice on Pharmacokinetics of Theophylline in Rat Plasma FABAD journal of Pharmaceutical sciences, 44(1), 9-16
  • Israa H. Al-Ani#, Ashok K. Shakya, Samira F. Hassan (2019) DEVELOPMENT AND VALIDATION OF METHOD OF ANALYSIS FOR A PROPOSED COMBINATION OF AMOXICILLIN AND IBUPROFEN IN ORAL DOSAGE FORM USING HPLC Journal of Global Trends in Pharmaceutical Sciences , 10 (2): 6152 - 6159
  • Mohammad Abdulla1, Eyad Mallah1, Wael Abu Dayyih1, Walid Abu Rayyan1, Feras Darwish El-Hajji2, Mona Bustami, Kenza Mansour1, Israa Al-Ani3, Nisreen Seder4 and Tawfiq Arafat1 (2018) Influence of Energy Drinks on Pharmacokinetic Parameters of Sildenafil in Rats Biomedical & Pharmacology Journal, Vol. 11(3), p. 1317-1328
  • Saif S Abbas, Israa H. Al-Ani,Wael AbuDayyih, Ghaleb Oriquat, Samira F Hassan (2018) Investigation of Possible Pharmacokinetic Interaction Between Ivabradine and Carvedilol in Rats Using High Performance Liquid Chromatography/Mass Spectroscopy Biomedical & Pharmacology Journal, Vol. 11(1), 311-324 (2018)
  • Wael Abu Dayyih1*, Zainab Zakarya1, Alice Abu Dayyih2, Israa Al-Ani3 (2018) Reversed Phase HPLC for a Validation and Determination of Udenafil (Zydena®) and Dapoxetine (Priligy®) Simultaneously in Tablet Dosage Form in Jordanian Market Der Pharma Chemica, 10(4): 68-74
  • (2018) workshop on mixing pharmaceutical product East Meditranean Pharmaceutical Symposium,
  • (2017) pH-independent extended release matrix tablet using propranolol hydrochloride as model drug. 3rd. International congress of the Greek local chapter of the controlled release society(CRS),
  • Faisal K. AL-Harthy1, Muayed A. Shehab1, Israa H. Al-Ani2, (2016) Development and Optimization of pH-Independent Extended Release Matrix Tablet of Propranolol Hydrochloride Using Eudragit RSPO by Hot Melt Granulation American Journal of Pharmacy and Pharmacology, 2015; 2(5): 52-60
  • (2016) FORMULATION OF LEVOFLOXACIN AS ORODISPERSIBLE TABLETS USING A READY-MADE BLEND OF EXCIPIENTS COMPARED WITH CLASSIC FORMULATION STRATEGIES Industrial Pharmacy and Pharmacovigillance,
  • Riad Awad , Eyad Mallah , Israa Al-Ani , Wael Abu Dayyih *, Zainab Zakarya , Tawfiq Arafat (2016) Investigation of possible pharmacokinetic interaction of metformin with sugar replacement sweeteners in rats Journal of Applied Pharmaceutical Science , Vol. 6 (10), pp. 210-215, 2016
  • Israa H. Al-Ani*, Samira F. Hassan, Naeem M. Shalan, Anwar D. Maraqa and Ghaleb A. Oriquat (2016) Preparation of Ibuprofen as Pediatric Candies Journal of Pharmaceutical science and Research, Vol. 8(1), 2016, 29-34
  • WAEL A ABU DAYYIH1*, EYAD M MALLAH1, ISRAA H AL-ANI2, TAWFIQ A ARAFAT1 (2015) LIQUORICE BEVERAGE EFFECT ON THE PHARMACOKINETIC PARAMETERS OF ATORVASTATIN, SIMVASTATIN, AND LOVASTATIN BY LIQUID CHROMATOGRAPHY-MASS SPECTROSCOPY/MASS SPECTROSCOPY Asian Journal of Pharmaceutical Sciences, Vol 9, Issue 2, 2016
  • ISRAA H. AL-ANI (2015) FORMULATION OF LEVOFLOXACIN AS ORODISPERSIBLE TABLETS USING A READY-MADE BLEND OF EXCIPIENTS COMPARED WITH CLASSIC FORMULATION STRATEGIES International Journal of Pharmacy and Pharmaceutical Sciences, Vol 7, Issue 10, 2015
  • Moh'd Salemaldajeha, Eyad Mallaha*, Riad Awada, Wael Abu Dayyiha, Feras Darwish Elhajjib, Israa H. Al-anic, Basmah A. Othmana and Tawfiq Arafata (2015) Determination of carbamazepine in rat plasma in the presence of licorice juice by using HPLC and its pharmacokinetic applications Journal of Chemical and Pharmaceutical Research, 2015, 7(12):116-126
  • Naeem Shalan, Abdulrahman Al-Bazzaz, Israa Al-Ani*, Fadi Najm, Mohammad Al-Masri (2015) Effect of Carbon Dioxide Therapy on Diabetic Foot Ulcer Journal of Diabetes Mellitus,, 2015, 5, 284-289
  • (2014) Coating potential of new coating formula (SEPICOAT TM) as an immediate release film coating material. 9th.World Meeting on Biopharmaceutics and Pharmaceutical Technology (PBP),
  • (2014) Coating potential of new modified starch coating materials ASU-Pharmacy First National Conference,
  • Fulla M. Alghabban, Israa H. Al Ani, Samira F. Hassan (2014) TASTE MASKING OF PRIFINIUM BROMIDE IN ORODISPERSIBLE TABLETS International journal of pharmacy and pharmaceutical sciences/, Vol.6 issue 8 pp.315-319
  • (2013) Preparation, Characterization and Release Study of Microspheres Loaded with Mychophenolic Acid Using 5th.BBBB International Conference (From Drug Discovery and Formulation Strategies to pharmacokinetics -pharmacodynamics),
  • (2013) TASTE MASKED ORO-DISPERSIBLE TABLETS AND ORAL SOLID DOSAGE FORM FOR PAEDIATRIC USE Formulating better medicines for children (5th. conference of Europian Paediatric Formulation Initiative),
  • FULLA M. AL-GHABBAN, ISRAA H. AL-ANI*, SAMIRA F. HASSAN, NAEEM SALAN (2013) FORMULATION OF PRIFINIUM BROMIDE AND PRIFINIUM BROMIDE –DICLOFENAC SODIUM COMBINATION AS ORODISPERSIBLE TABLETS International Journal of Pharmacy and Pharmaceutical Sciences, Vol 5, Suppl 2, pp 652-659
  • Israa Al-Ani1, Alaa Abdulrasool2 and Jabar Faraj (2013) Preparation, Characterization and Release Study of Microspheres Loaded with Mychophenolic Acid Using Different Ratios of Two Molecular Weight PLGA Journal of Materials Science and Engineering, A 3 (12) (2013) 820-830
  • issra H. Al-Ani, Alaa A. Abdulrasool (2000) compatibility study of the Formulated chlorpromazine HCl with some I.V fluids, Journal of Iraqi Pharmaceutical sciences, 65-71

CONFERENCES AND WORKSHOPS

Conference Title Type of Participation Location Date
9th.World Meeting on Biopharmaceutics and Pharmaceutical Technology (PBP) Paper/Poster Lisboa/Portugal March / Present
nevigating the ICH generic drug draft guideline M13A bioequivalence for immediate release oral solid dosage form Attendance USA (online) May / 2023
ASU-Pharmacy Forth National Conference (Recent trends in postgraduate studies) Paper/Poster Jordan January / 2019
East Meditranean Pharmaceutical Symposium Paper/Poster Jordan July / 2018
3rd. International congress of the Greek local chapter of the controlled release society(CRS) Paper/Poster Athens/Greece June / 2017
Industrial Pharmacy and Pharmacovigillance Paper/Poster AND Participate in the organization of Conference Dubai, UAE April / 2016
ASU-Pharmacy First National Conference Paper/Poster Amman,Jordan December / 2014
Formulating better medicines for children (5th. conference of Europian Paediatric Formulation Initiative) Paper/Poster Barcelona/ Spain September / 2013
5th.BBBB International Conference (From Drug Discovery and Formulation Strategies to pharmacokinetics -pharmacodynamics) Paper/Poster Athens/Greece September / 2013
the international conference of health care. Participate in the organization of Conference A-Ahliyya Amman University, Jordan May / 2011
The Eight conference and the diamondUbil for college of pharmacy,University of Baghdad Attendance Baghdad, Iraq February / 2011

THESIS SUPERVISION

Title Location Date
Improving Drug Loading and Dissolution Rate of Erlotinib by Supersaturated Lipid Based -Silica Hybrid Drug Delivery System Compared to Lipid Based Formulation, A Comparative Study Al-Ahliyya Amman University 2023
Application of Quality-by-Design (QbD) Approach for Enhancing the Solubility and Dissolution Rate of loratadine using Tocopheryl polyethylene glycol 1000 succinate (TPGS) in tablet dosage form. Al-Ahliyya Amman University 2023
Preparation and Evaluation of Ubiquinone (Co-enzyme Q10) Antiaging Serum for Skin Care Al-Ahliyya Amman University 2023
Preparation and characterization of Camptothecin -β-cyclodextrin complex coated with PEGylated Rutin phytosmes Al-Ahliyya Amman University 2023
Enhancement of Dissolution of Olanzapine in Tablet Dosage Form by Liquid-Solid Technique. Al-Ahliyya Amman University 2023
Preparation and Evaluation of SBA-16, ZSM-5 and MCM-41 Mesoporous Silica Nanoparticles as Drug Delivery System for Carvedilol Al-Ahliyya Amman University 2022
Measurement of Bioavailability of Alectinib Inclusion Complex as Oral Dosage Form in Animal Model. Al-Ahliyya Amman University 2022
Formulation and evaluation of topical combination therapy of clofibrate and azelaic acid for treatment of acne. Al-Ahliyya Amman University 2022
Formulation and In Vitro Evaluation of ZSM-5 Nanoparticles loaded with Gefitinib for Treatment of Non-Small Cell Lung Carcinoma. Al-Ahliyya Amman University 2022
Evaluation the Impact of Orange Juice on Apixaban Pharmacokinetics in healthy rats Al-Ahliyya Amman University 2022
Improvement of Solubility and Dissolution Rate of Apixaban by Inclusion Complex (β-Cyclodextrin and Hydroxypropyl β-Cyclodextrin) Al-Ahliyya Amman University 2022
Formulation and in vitro evaluation Telmisartan-Hydrochlorothiazide combination ionic liquid as oral dosage form. Al-Ahliyya Amman University 2022
Formulation and In Vitro Evaluation of Telmisartan-Amlodipine Combination Ionic Liquid as Oral Dosage Form Al-Ahliyya Amman University 2022
Preparation and evaluation of chitosan nanoparticles loaded with Ivabradine Al-Ahliyya Amman University 2022
Formulation and Evaluation of Retinol and Vitamin E as Nanoemulsion for Skin Care. Al-Ahliyya Amman University 2022
Phosphodiestrase 5 inhibitors detection in traditional herbal mixtures used for erectile dysfunction in spices stores in Jordan by High-performance liquid chromatography (HPLC) technique. Al-Ahliyya Amman University 2022
Preparation and Evaluation of SBA-16 Nanoparticles Loaded with Alectinib for Treatment of Non-Small Cell Lung Cancer Al-Ahliyya Amman University 2022
Studying Pharmacokinetic interaction of Esomeprazole and apixaban in rats Al-Ahliyya Amman University 2021
Preparation and In-vitro Evaluation of Metformin-Vildagliptin combination as Oro-dispersible Tablets Al-Ahliyya Amman University 2021
FORMULATION AND IN-VITRO EVALUATION OF METFORMIN-TADALAFIL COMBINATION AS ORO-DISPERSIBLE TABLETS (ODT) Al-Ahliyya Amman University 2021
FORMULATION AND IN VITRO EVALUATION OF ETORICOXIB-OMEPRAZOLE COMBINATION AS ENTERIC -COATED TABLETS Al-Ahliyya Amman University 2021
Preparation and Evaluation of Oroslippery Tablets Contain Irbesartan and Hydrochlorothiazide Combination for Dysphagia Patients Al-Ahliyya Amman University 2021
IMPROVEMENT OF SOLUBILITY AND DISSOLUTION RATE OF ALECTINIB BY INCLUSION COMPLEX (β-CYCLODEXTRIN AND HYDROXYPROPYL β-CYCLODEXTRIN) Al-Ahliyya Amman University 2021
Evaluation the Impact of Orange Juice on Rosuvastatin Pharmacokinetics in Healthy Rats Al-Ahliyya Amman University 2021
A new pharmaceutical preparation comprising metformin, vitamin B1,vitamin Be, vitamin B12 and folic acid as an oral tablet dosage form. Al-Ahliyya Amman University, Petra university 2017
Investigation of pharmacokinetic interaction between ivabradine and carvedilol in rats using HPLC/MS Al-Ahliyya Amman University 2016
Comparative Study of coating potential of sepicoat TM and Opadry white Y and OpadryII white in immediate release oral tablets. Al-Ajliyya Amman University 2014
Formulation and Evaluation of Prifinium bromide amd Profinium bromide-Diclofenac sodium combination as orodispersible tablet. Al-Ahliyya Amman University 2013

AWARDS AND SCHOLARSHIP

Title Location Date
Award of University of Baghdad for first rank Ph.D graduants University of Baghdad 2007
Award of President of Republic of Iraq for first rank gradaunt in Pharmacy Presidency of Repblic of Iraq 1992

Al-Ahliyya Amman University

Email: Public@ammanu.edu.jo

 

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