• pharmaceutical chemistry
• Organic chemistry
• Medicinal chemistry
• Drug design
• Biochemistry
• General Chemistry
• Physical Pharmacy
• Research graduate project

• Drug Bioconjugation, Drug delivery systems

• Tabarek H. Mahmood, Ali Al-Samydai, Mazen Al Sulaibi, Moath Alqaraleh, Anas Ibrahim Abed, Naeem Shalan, Alaa Alsanabrah, Shrouq Taiseer Alsotari, Hamdi Nsairat, Walhan Alshaer (2023) Development of Pegylated Nano-Phytosome Formulation with Oleuropein and Rutin to Compare Anti-Colonic Cancer Activity with Olea Europaea Leaves Extract Chemistry and Biodiversity, Volume20, Issue8 August 2023 e202300534
• Hamdi Nsairat 1, Dima Khater 2, Fadwa Odeh 3, Areej M. Jaber 1, Mazen A.M. Al Sulaibi 1, Walhan Alshaer 4, Abeer Al Bawab 3 5, Mohammad S. Mubarak (2023) Phytosomes: a modernistic approach to the delivery of herbal drugs Elsiver, 2023, Pages 301-355
• Hamdi Nsairat a, Zainab Lafi a, Mazen Al-Sulaibi a, Lobna Gharaibeh a, Walhan Alshaer (2023) Impact of nanotechnology on the oral delivery of phyto-bioactive compounds Food Chemistry, Volume 424, 30 October 2023, 136438
• Ali Al-Samydai Moath Al Qaraleh Khaldun M. Al Azzam Amal Mayyas Hamdi Nsairat Maha N. Abu Hajleh Lidia K. Al-Halaseh Nehaya Al-Karablieh Amal Akour Fatima Alshaik Walhan Alshaer (2023) Formulating co-loaded nanoliposomes with gallic acid and quercetin for enhanced cancer therapy Heliyon, VOLUME 9, ISSUE 6, E17267, JUNE 2023
• Mohamed El-Tanani ,Hamdi Nsairat ,Vijay Mishra,Alaa A. A. Aljabali ,Ángel Serrano-Aroca and Murtaza M. Tambuwala (2023) Ran GTPase and Its Importance in Cellular Signaling and Malignant Phenotype International Journal of Molecular Sciences, 2023, 24(4), 3065
• Maram Kutkut, Ashok K. Shakya , Hamdi Nsairat1 , Mohamed El-Tanani (2023) Formulation, development, and in vitro evaluation of a nanoliposomal delivery system for mebendazole and gefitinib Journal of Applied Pharmaceutical Science, 13,001-014
• Fedaa Adaileh a, Walhan Alshaer b, Hamdi Nsairat c, Dana A. Alqudah b, Suha Wehaibi b, Fadwa Daoud b, Rula Al-Buqain b d, Shrouq Alsotari b, Abeer Al Bawab a, Fadwa Odeh a (2023) Curcumin-loaded γ -cyclodextrin-grafted hyaluronic acid nanoassimblies: In vitro investigation of anti-proliferative, wound healing, and anti-inflammatory potential Journal of Drug Delivery Science and Technology, Volume 87, September 2023, 104886
• Hamdi Nsairat a, Mazen Al-Sulaibi a, Walhan Alshaer (2023) PEGylated nanoassemblies composed of edelfosine and fulvestrant drugs: In vitro antiproliferative effect against breast cancer cells Journal of Drug Delivery Science and Technology, Volume 85, August 2023, 104612
• Hamdi Nsairat,Abed Alqader Ibrahim,Areej M. Jaber,Sharif Abdelghany,Randa Atwan,Naeem Shalan,Hiba Abdelnabi,Fadwa Odeh,Mohamed El-Tanani &Walhan Alshaer show less (2023) Liposome bilayer stability: emphasis on cholesterol and its alternatives Journal of Liposome Research, 1-25
• Mohamed El-Tanani a b, Angela Platt-Higgins c, Hamdi Nsairat a, Ismail I. Matalka d e, Khaled Abdul-Aziz Ahmed a, Shu-Dong Zhang f, Walhan Alshaer g, Abdalla Awidi g, Kyle B. Matchett h, Alaa A. Aljabali i, Vijay Mishra j, Ángel Serrano-Aroca k, Murtaza M. Tambuwala l, Philip S. Rudland (2023) Development and validation of Ran as a prognostic marker in stage I and stage II primary breast cancer Life Sciences, Volume 329, 15 September 2023, 121964
• Mohamed El-Tanani a b, Hamdi Nsairat a, Alaa A. Aljabali c, Ángel Serrano-Aroca d, Vijay Mishra e, Yachana Mishra f, Gowhar A. Naikoo g, Walhan Alshaer h, Murtaza M. Tambuwala (2023) Role of mammalian target of rapamycin (mTOR) signalling in oncogenesis Life Sciences, Volume 323, 15 June 2023, 121662
• Mohamed El-Tanani, Hamdi Nsairat, Ismail I. Matalka, Alaa A. A. Aljabali, Vijay Mishra, Yachana Mishra, Gowhar A. Naikoo, Sai Raghuveer Chava, Nitin B. Charbe & Murtaza M. Tambuwala (2023) Impact of exosome therapy on pancreatic cancer and its progression Medical Oncology, 40, Article number: 225 (2023)
• Hamdi Nsairat , Walhan Alshaer , Fadwa Odeh , Ezzaldeen Esawi , Dima Khater d, Abeer Al Bawab , Mohamed El-Tanani , Abdalla Awidi , Mohammad S. Mubarak (2023) Recent advances in using liposomes for delivery of nucleic acid-based therapeutics OpenNano, Volume 11, May 2023, 100132
• by Ashok K. Shakya 1,2,*ORCID,Mazen Al-Sulaibi 1,2,Rajashri R. Naik 2,3,Hamdi Nsairat 1,2,Sara Suboh 1 andAbdelrahman Abulaila 1 (2023) Review on PLGA Polymer Based Nanoparticles with Antimicrobial Properties and Their Application in Various Medical Conditions or Infections Polymers, Volume 15 Issue 17 10.3390/polym15173597
• Hamdi Nsairat , Dima Khater , Usama Sayed , Fadwa Odeh , Abeer Al Bawab , Walhan Alshaer (2022) Liposomes: structure, composition, types, and clinical applications Heliyon, e09394
• Walhan Alshaer ,Hamdi Nsairat ,Zainab Lafi ,Omar M. Hourani ,Abdulfattah Al-Kadash ,Ezaldeen Esawi and Alaaldin M. Alkilany (2022) Quality by Design Approach in Liposomal Formulations: Robust Product Development Molecules, 2023, 28(1), 10
• Fedaa Adaileh ,Walhan Alshaer ,Hamdi Nsairat ,Dana A. Alqudah ,Areej M. Jaber and Abeer Al Bawab (2022) Synthesis of Mono-Amino Substituted γ-CD: Host–Guest Complexation and In Vitro Cytotoxicity Investigation Molecules, 2022, 27(5), 1683
• Mohammad A. Obeid ,Hamid A. Bakshi ,Walhan Alshaer Raed M. Ennab ,Bahaa Al-Trad ,Wesam Al Khateeb ,Khalid M. Al-Batayneh ,Abdulfattah Al-Kadash,Shrouq Alsotari ,Hamdi Nsairat and Murtaza M. Tambuwala (2022) Synthesis, Characterization, and Assessment of Anti-Cancer Potential of ZnO Nanoparticles in an In Vitro Model of Breast Cancer Molecules, 2022, 27(6), 1827
• Hamdi Nsairat, Ismail S. Mahmoud, Fadwa Odeh, Duaa Abuarqoub, Hafsa Al-Azzawi Rand Zaza, Malak I. Qadri, Said Ismail, Abeer Al Bawab, Abdalla Awidi and Walhan Alshaer (2022) Grafting of Anti-nucleolin Aptamer into Preformed and Remotely Loaded Liposomes Through Aptamer-Cholesterol Post-insertion RSC advance, 10, 36219-36229
• Hamdi Nsairat, Walhan Alshaer, Abdulfattah Al-Kadash, Wissam Helal, Lubna Alrawashdeh, Anthony Day, Khaleel I. Assaf, Rola Hassouneha, Fadwa Odeh and Abeer Al Bawab (2022) Cinnamaldehyde–cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity RSC Advanves, 12, 7540-7549
• Ismail Sami Mahmoud*, Ma’mon M. Hatmal, Duaa Abuarqoub, Ezaldeen Esawi, Hiba Zalloum, Suha Wehaibi, Hamdi Nsairat, and Walhan Alshaer* (2021) 1,4-Naphthoquinone Is a Potent Inhibitor of IRAK1 Kinases and the Production of Inflammatory Cytokines in THP-1 Differentiated Macrophages ACS OMEGA, https://doi.org/10.1021/acsomega.1c03081
• Dima Khater ,Hamdi Nsairat ,Fadwa Odeh ,Mais Saleh ,Areej Jaber 2,Walhan Alshaer ,Abeer Al Bawab and Mohammad S. Mubarak (2021) Design, preparation, and characterization of effective dermal and transdermal lipid nanoparticles: A review Cosmetics, 8(2), 39
• Hamdi Nsairat Dima Khater Fadwa Odeh Fedaa Al-Adaileh Suma Al-Taher Areej M. Jaber Walhan Alshaer Abeer Al Bawab Mohammad S.Mubarak (2021) Lipid nanostructures for targeting brain cancer Heliyon, Volume 7, Issue 9, September 2021, e07994
• Hamdi Nsairat, Areej Jaber and Mazen Alsulaibi (2021) Biosensors for Fungal Detection Journal of Pure and Applied Microbiology, 15(4):1719-1726
• Zainab Lafia, Walhan Alshaer, Ma'mon M. Hatmal, Malek Zihlif, Dana A. Alqudah, Hamdi Nsairat, Hanan Azzam, Talal Aburjai, Yasser Bustanji and Abdalla Awidi (2021) Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells RSC Advanves, 11, 29164-29177
• Odeh, F., Nsairat, H., Alshaer, W., Alsotari, S., Buqaien, R., Ismail, S., Awidi, A. and Al Bawab, A. (2020) Remote loading of curcumin-in-modified β-cyclodextrins into liposomes using a transmembrane pH gradient RSC Advances, 9, 37148-37161
• (2019) Best scientific Poster 16th Jordanian conference of chemistry,
• . Odeh, F., Nsairat, H., Alshaer, W., Ismail, M. A., Esawi, E., Qaqish, B., Bawab, A. A. and Ismail, S. I. (2019) Aptamers Chemistry: Chemical Modifications and Conjugation Strategies Molecules, 25., Molecules, 25.
• Alshaer, W., Zraikat, M., Amer, A., Nsairat, H., Lafi, Z., Alqudah, D. A., Al Qadi, E., Alsheleh, T., Odeh, F., Alkaraki, A., Zihlif, M., Bustanji, Y., Fattal, E. and Awidi, A. (2019) Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma RSC Advances, 9, 30976-30988
• Khalid, K, Nsairat, H , Zhang. J, (2016) The Presence of Interleukin 18 Binding Protein Isoforms in Chinese Patients with Rheumatoid Arthritis AMIS Medical Science , Volume 3, Issue 1, 103-113.
• Waled Amen Mohammed Ahmed, , Sawsan Mustafa Abdalla , Elsadig Yousif Mohamed , Osman Babiker Osman , Hamdi Nouri Najeeb Alnsairat (2015) Home Accidents Rate Among Under-Five Children and Predisposing Factors in Khartoum International Journal of Preventive Medicine Research, Vol. 1, No. 5, 2015, pp. 267-269

Published Books:

• Chapter 12 - Phytosomes: a modernistic approach to the delivery of herbal drugs (2023) Advanced and Modern Approaches for Drug Delivery Elsevier
• (2022) Aptamers in Theranostic Bionanomaterials Bentham
• Aptamers in Theranostic Bionanomaterials (2022) Bionanotechnology: Next-Generation Therapeutic Tool Bentham Science Publishers
• Clinical use and future perspective of aptamers (2022) Aptamers Engineered Nanocarriers for Cancer Therapy Elsevier