Dr. Sima Zein

Associate Professor

Major: Molecular and Cell Biology

Departemnt: Medical Laboratory Sciences Department

Faculty: Faculty of Allied Medical Sciences



Extention: -



  • Molecular Biology
  • Molecular Cell Biology
  • Genetics
  • Research project
  • Molecular Genetics
  • Medical Terminology
  • Medical Virology
  • Seminar
  • Clinical Laboratory Orientation
  • Developmental Biology
  • Bio-ethics
  • General Biology
  • Science and Society


Rank University Country Date
Associate Professor American University of Madaba Jordan 2021
Assistant Professor American University of Madaba Jordan 2012
Lecturer University of Texas at Dallas USA 2004


Degree Institute Specialization Country Date
ماجستير The University of Texas at Dallas Molecular and Cell Biology الولايات المتحدة الأمريكية June / 2000
دكتوراة The University of Texas at Dallas Molecular and Cell Ciology الولايات المتحدة الأمريكية May / 2004
بكالوريوس Yarmouk University Biological Sciences الأردن June / 1991


Job Title Institute Time Period
Teaching/research Al-Ahliyya Amman University October / 2023 - January / Present
Teaching/research American University of Madaba, Madaba/Jordan. September / 2012 - September / 2023
Research scientist University of Texas Southwestern Medical Center at Dallas, Texas/USA. January / 2012 - September / 2012
Postdoctoral fellow University of Texas Southwestern Medical Center at Dallas, Texas/USA. January / 2009 - January / 2011
Postdoctoral fellow University of Texas Southwestern Medical Center at Dallas, Texas/USA. January / 2007 - January / 2009
Research engineer University of Texas at Dallas, Texas, USA May / 2004 - December / 2006
lecturer University of Texas at Dallas, Texas, USA May / 2004 - May / 2005


  • Virology
  • Neurology
  • Biotechnology
  • Thalassemia


  • Sima Zein, Wajdy J. Al-Awaida, Olga M. Yuldasheva, Andrey S. Khakimov, Sergey M. Chibisov, Yulia Gushchina, Omar A. Al bawareed, Vladimir I. Torshin, Еlena В. Yakunin, Hamzeh J. Al-Ameer, Irina V.Podoprigora (2021) Influence of geographic conditions on body length of male newborns in Kyrgyzstan International Journal of Biometeorology, 65(12):2053-2057, 2021
  • Sima Zein, Sarah B Abdallah, Ahmed Al-Smadi, Omar Gammoh, Wajdy J. Al-Awaida, Hanan J. Al-Zein. (2021) Factors associated with the unwillingness of Jordanians, Palestinians and Syrians to be vaccinated against COVID-19 PLOS Neglected Tropical Diseases, Dec 9;15(12): e0009957, 2021.
  • Omar Gammoh, Ahmed Al-Smadi, Mohammad Qassem Shawagfeh, J Kasawneh, S Malkawi, Sima Zein (2021) The Clinical Difference between Gabapentin and Pregabalin: Data from a Pilot Comparative Trial Reviews on Recent Clinical Trials, 16(3):279-287. 2021
  • Omar S. Gammoh , Ahmed Al-Smadi , Malak Tayfur , Manal Al-Omari , Walid Al-Katib , Sima Zein & Hrayr Attarian (2020) Syrian female war refugees: preliminary fibromyalgia and insomnia screening and treatment trends International Journal of Psychiatry in Clinical Practice, 24(4):387-391. 2020
  • Fadwa Hammouh, Sima Zein, Rula Amr, Hadeel Ghazzawi,Dina Muharib, Dalya Saad, Hadil Subih (2020) Assessment of dietary selenium intake of Jordanian adults in Madaba: A cross-sectional study Nutrition and Food Science, 51(3):494-506, 2021
  • Sima Zein, Fadwa Hammouh, Basem Dababneh , Omar Gammoh, Ahmed Al-Smadi (2020) In vitro and in vivo antibacterial activity of C. speciosus rhizome extract on resistant bacteria Pakistan Journal of Biological Sciences, 23(7):931-939. 2020
  • Al-Awaida W., Jawabrah Al-Hourani B., Akash M, Talib WH, Zein S, Falah R (2018) In vitro anticancer, anti-inflammatory, and antioxidant potentials of Ephedra aphylla Journal of Cancer Research and Therapeutics, 14(6):1350-1354. 2018.
  • Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber Y, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, Stüve O (2012) Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01 – Relevance for diagnosing and monitoring patients with neuromyelitis optica JAMA Neurology, 69(9):1125-31. 2012
  • Denton P, Othieno F, Martinez-Torres F, Zou W, Krisko J, Fleming E, Zein S, Powell D, Kwak Y, Welch P, Kay M, Payne D, Gallay P, Appella E, Estes J, Lu M, Garcia-Martinez JV. (2011) Topically Applied 1% Tenofovir in Humanized BLT Mice Using the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection Validating the BLT Model for the Evaluation of New Microbicide Candidates Journal of Virology, 85 (15):7582-7593. 2011.
  • Zein S., Li W, Ramakrishnan V, Lou TF, Sivanand S, Mackie A, Pace BS (2010) Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line Experimental Biology and Medicine, 235:1385-1394. 2010.
  • S Kodeboyina, S Zein, M Lee, P Balamurugan, X Yao, B Pace (2008) Role of Cjun in Gγ-Globin Gene Trans-Activation Blood, 11(112):1870. 2008
  • Betty S Pace, Moo Seung Lee, Xia Yao, Sima Zein, Jose Sangerman (2007) Histone deacetylase inhibitors induce γ-globin expression by p38 MAPK-mediated CREB and ATF-2 activation Blood Cells, Molecules, and Diseases , 38(2): 166-166. 2007
  • Sangerman H, Lee M.S., Yao X., Oteng E., Hsiao C.H., Li W., Zein S., Ofori-Acquah S.F., Pace BS (2006) Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves γ-globin activation by CREB1 and ATF-2 Blood, 108 (10): 3590–3599. 2006.
  • Pace BS, Zein S (2006) Understanding mechanisms of gamma-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction Developmental Dynamics, 235(7):1727-37. 2006
  • Zein S. and Levene SD (2005) Structural aspects of RecA-dependent homologous strand exchange involving human telomeric DNA Biochemistry, 44, 4817-4828. 2005.
  • Vash B., Phung N., Zein S., and DeCamp D (1998) Three complement-type repeats of the low-density lipoprotein receptor-related protein define a common binding site for RAP, PAI-1, and lactoferrin Blood, 92, 3277-3285. 1998


Conference Title Type of Participation Location Date
Organizing committee member in WCLER-2022 Dubai/UAE conference Participate in the organization of Conference DUBAI December / 2022
4th Stem Cells and Cellular Therapy Conference (2018), King Abdullah International Medical Research Center Riyadh, KSA. Attendance KSA January / 2018
The Jordan Society of Scientific Research 8th conference on (2017) Amman, Jordan. Attendance Jordan April / 2017
World Science Forum (2017), Dead Sea, Jordan. Attendance Jordan January / 2017
Advances in Drug Discovery and Development conference (2015). Participate in the organization of Conference Jordan January / 2015
Oral presentation at the 15th Scientific Congress of the Jordanian Pharmacists Association, Amman, Jordan (2014). Participate in the organization of Conference Jordan January / 2014
• Oral presentation at the American Academy of Neurology annual meeting, Toronto, Canada (2010). Participate in the organization of Conference Canada January / 2010


Title Location Date
Guest editor, PLOS Neglected Tropical Diseases, 2021-now. Jordan 2024
• MIRROR fellowship (Minority Recruitment, Retention and Opportunity for Researchers program), University of Texas at Dallas (2005). USA 2024
Advisory board member, WCLER- 2022 Dubai, UAE Conference, December, 2022. Dubai 2022
Awarded a research grant from the American University of Madaba (2020) Jordan 2020
Editor, Reviews on Recent Clinical Trials Journal, 2019, 1 year. Jordan 2019
Awarded a research grant from the American University of Madaba (2016). Jordan 2016
Postdoctoral training certificate in Advanced Research (2011). USA 2011

Al-Ahliyya Amman University

Email: Public@ammanu.edu.jo


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