Al-Ahliyya Amman University
Prof. Dr. Manal Ahmad Abbas
Professor
Major: physiology
Department: Medical Laboratory Sciences Department
Faculty: Faculty of Allied Medical Sciences
Email:
Extention: -
Profiles:
COURSES TAUGHT
- Microtechnique
- General Biology
- Anatomy & Histology
- Physiology
- Advanced clinical endocrinology
ACADEMIC RANKS
| Rank | University | Country | Date |
|---|---|---|---|
| Professor | Al-Ahliyya Amman University | Jordan | 2022 |
QUALIFICATION
| Degree | Institute | Specialization | Country | Date |
|---|---|---|---|---|
| دكتوراة | The University of Jordan | Physiology | الأردن | July / 2011 |
| Masters Degree | The University of Jordan | Biological Sciences | الأردن | July / 1997 |
| Bachelors Degree | The University of Jordan | Medical and Biological Analysis | الأردن | January / 1994 |
WORK EXPERIENCE
| Job Title | Institute | Time Period |
|---|---|---|
| Faculty member | Al-Ahliyya Amman University | September / 2012 - November / Present |
| Assistant professor | Al Zaytoonah University of Jordan | November / 2011 - November / 2012 |
| Laboratory supervisor | Zarqa Private University | January / 1997 - November / 1997 |
| Research assistant | The university of Jordan | January / 1994 - November / 1994 |
RESEARCH INTERESTS
- drug discovery
- Fertility Research
- Molecular mechanisms of hormone action
- Anticancer effect of natural products
RESEARCHES AND PUBLICATIONS
- Shraim, A.; Abbas Manal A. (2025) Transient receptor melastatin channel in colorectal cancer: pathophysiological mechanisms and a promising drug target Cancer Chemotherapy and Pharmacology, 95, 2025
- OM Al-Sanabra, MA Abbas, WJ Hazà, AA Hazàa, AK Al Tibi (2025) Coagulation and Fibrinolysis Dysregulation in β-Thalassemia Major: Potential Impact of Splenectomy and Medications on Thrombotic Risk Clinical and Applied Thrombosis/Hemostasis, 31, 10760296251359291
- Fadi G. Saqallah1, Manal A. Abbas2, Belal O. Al-Najjar3,4, Aya Y. Al-Kabariti3,4, Muhammad Yusuf5,6, Omar A. Abdulwahed7, Noor A. Barakat8 and Mohammad Alsalem9,* (2025) Ononin’s Antagonistic Activity towards TRPV1: Insights from Molecular Dynamics and Capsaicin-Evoked Calcium Response in DRG Neurons Current Medicinal Chemistry, in press, 2025
- MA Abbas, AY Al‐Kabariti, R El‐Rayyes, R Obeidat, AA Al‐Rayyes (2025) TRPC1 and TRPC5 in Colorectal Cancer: Mechanisms, Prognostic Markers, and Therapeutic Targets Drug Development Research, 86 (5), e70123, 2025
- Haya F Al-Khalaila 1 2, Manal A Abbas 1, Muna A Almaharma 2 (2025) Disseminated Intravascular Coagulation in Pediatric Acute Leukemia: Prevalence, Laboratory Features, and Prognostic Significance of ISTH Score Int J Lab Hematol . , Online ahead of print.
- Basma Ateeq Abu msafer, Manal A. Abbas, Walhan al Shaer, Sally Arafat (2025) Enhanced Platelet Activation Induced by Palbociclib Treatment in MCF-7 Breast Cancer Cells Jordan Journal of Pharmaceutical Sciences, 18(1), 2025: 10-20
- FG Saqallah, BO Al-Najjar, AY Al-Kabariti, MA Abbas (2025) Novel acridone derivatives as potential P2Y12 receptor inhibitors: integrating computational modeling and experimental analysis Journal of Biomolecular Structure and Dynamics, 1-10, 2024
- Ahmad Saleh Al-Radaideh, Manal A. Abbas, Aya Y. Al-Kabariti , Moath Alqaraleh , Razan Madi , Razan Obeidat (2025) Rhoifolin potentiates the anti-cancer activity of doxorubicin in MDA-MB-231 triple-negative breast cancer cells pharmacia, 72(1), 2025:1-9
- Noura Abedalnaser Alqalalwah, Manal M. Abbas, Manal A. Abbas, Razan Obeidat and Randa El-Rayyes (2025) Genistein potentiated the cytotoxic effect of entinostat in colorectal cancer cell lines Research in Pharmaceutical Sciences,, 20(3), 2025, 408-415
- MANAL M. ABBAS , MANAL A. ABBAS , WAEL MOHAMEDY AFIFI, YASSER IBRAHIM KANDIL (2024) FLAVONOID-RICH EXTRACT OF VARTHEMIA IPHIONOIDES INCREASED LOW-DENSITY LIPOPROTEIN RECEPTOR AND DECREASED HYDROXYMETHYLGLUTARYL COA REDUCTASE EXPRESSION IN HEPG2 CELLS Farmacia, 72(3)
- Nada Mdanat, Manal Abbas (2024) Prevalence of anemia among patients with subclinical and clinical hypothyroidism in Jordan JJBS, 17
- Khalid AlqaisiKhalid AlqaisiManal Ahmad AbbasManal Ahmad AbbasRand Alshawawreh (2024) Chrysin dose-dependent effects on steroidogenesis in female BALB/c mice: In vivo study of adrenal, ovarian, and uterine hormone regulation Pharmacia, 71
- Raheeq Khairy Abdullah, Reem A. Issa, Mahmoud Abu-Samak, Beisan A. Mohammad, Manal A. Abbas, Shady Helmi Awwad (2024) Nephroprotective effects of Equisetum ramosissimum L. extract in streptozotocin-induced diabetic rats Pharmacia, 71
- RS Al Taher, MA Abbas, K Halahleh, MA Sughayer (2024) Correlation Between ImageJ and Conventional Manual Scoring Methods for Programmed Death-Ligand 1 Immuno-Histochemically Stained Sections Technology in Cancer Research & Treatment, 23
- Manal A. Abbas , Aya Y. Al-Kabariti , Chris Sutton (2024) Comprehensive understanding of the role of GPER in estrogen receptor-alpha negative breast cancer The Journal of Steroid Biochemistry and Molecular Biology , 241
- El-Rayyes R, Abbas MM, Obeidat R, Abbas MA. I (2023) Isorhamnetin decreased the expression of HMG-CoA reductase and increased LDL receptors in HepG2 cells Journal of Applied Pharmaceutical Science, 4;13(5):155-61.
- Randa El-Rayyes, Manal M Abbas, Razan Obeidat, Manal A Abbas (2023) Isorhamnetin decreased the expression of HMG-CoA reductase and increased LDL receptors in HepG2 cells Journal of Applied Pharmaceutical Science, in press
- Yaghmour YM, Said SA, Ahmad AM. (2023) Biochemical and hematological findings and risk factors associated with kidney impairment in patients with COVID-19. Journal of Medical Biochemistry. , 42(1):35.
- Abdulwahed O.A., Al-Najjar B.O., Abbas M.A. , Alsalem M. (2023) Analgesic effect of neohesperidin is mediated by TRPV1 antagonism. JPPres, in press
- AY Al-Kabariti, MA Abbas (2023) Progress in the understanding of estrogen receptor alpha signaling in triple-negative breast cancer: Reactivation of silenced ER-α and signaling through ER-α36 Molecular Cancer Research, 21
- Abbas MA, Al-Saigh NN, Saqallah FG. (2023) Regulation of adipogenesis by exosomal milk miRNA. Reviews in Endocrine and Metabolic Disorders. , 24(2):297-316.
- E Al-Khateeb, MA Abbas, MB Khader, MA Sughayer (2023) Programmed death-ligand 1 expression in diffuse large B-cell lymphoma is associated with poor prognosis The International Journal of Biological Markers, 141
- Al-Khateeb E, Abbas MA, Khader MB, Sughayer MA. (2023) Programmed death-ligand 1 expression in diffuse large B-cell lymphoma is associated with poor prognosis. The International Journal of Biological Markers., ;38(1):53-60.
- MA Abbas, KM Alqaisi, A Disi, NA Hameed (2022) Chrysin increased progesterone and LH levels, estrous phase duration and altered uterine histology without affecting aromatase expression in rat ovary Journal of Functional Foods , 89
- Al-Yousef RR, Abbas MM, Obeidat R, Abbas MA. (2022) Rhamnetin decreases the expression of HMG-CoA reductase gene and increases LDL receptor in HepG2 cells. Journal of Pharmacy & Pharmacognosy Research, 11(1):47-54.
- Al-naimat HH, Abbas MA, Aladily TN, ALmahaharmeh MA, ALmomani LM. (2022) Detection of Inherited Thrombophilic Mutations in Jordanian Children Suffering from Thrombotic Events. Jordan Journal of Biological Sciences, 15;15(5)
- Journal of Pure & Applied Microbiology (2022) Al-Halaseh LK, Sweiss MA, Issa RA, AlKassasbeh R, Abbas MA, Al-Jawabri NA, Hajleh MN, Al-Samydai AM. Nephroprotective Activity of Green Microalgae, Chlorella sorokiniana Isolated from Jordanian Water. , 1;16(4).
- Hasan A, Issa R, Al-Halaseh L, Abbas MA, Al-Jawabri N, Al-Suhaimat R. (2022) Investigation of the nephroprotective activity of Moringa peregrina leaves aqueous extract in mice. Pharmacia, 69(4):1095-102.
- Saqallah FG, Abbas MA, Wahab HA. (2022) Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease. Phytochemistry. , 7: 113362.
- Abbas, M. A., Kandil, Y. I., Disi, A. M., & Jaffal, S. M. (2019) Gastroprotective activity of Loranthus acaciae flower extract in a rodent model of ethanol-induced ulcer Applied physiology nutrition and metabolism, 44(12)
- Jaffal, S. M., & Abbas, M. A. (2019) Antinociceptive action of Achillea biebersteinii methanolic flower extract is mediated by interaction with cholinergic receptor in mouse pain models Inflammopharmacology, , 27(5), 1-8
- Mohammad Alsalem · Mansour Haddad · Sara A. Aldossary · Heba Kalbouneh · Ahmad Altarifi · Sahar M. Jaffal · Manal A. Abbas· Nour Aldaoud · Khalid El‑Salem (2019) Role of cannabinoid receptor 1 and the peroxisome proliferator-activated receptor α in mediating anti-nociceptive effects of synthetic cannabinoids and a cannabinoid-like compound. , 2019, 1-12. Inflammopharmacology, 27
- Abbas, M. A. (2019) Analgesic effect of Allium ampeloprasum: Evidence for the involvement of beta-adrenergic system Journal of Functional Foods, 57, 1-6
- Jaffal, S. M., Abbas, M. A., Alsalem, M., & Al-Najjar, B. O. (2019) Evidence for the involvement of opioid receptor in Ajuga chamaepitys action in chemical and thermal models of pain in BALB/c mice Medicinal chemistry research, 28(7), 992-999.
- Abbas, M. A., Jaffal, S. M. & Al-Najjar, B. O. (2019) Analgesic and Anxiolytic Activities of Achillea biebersteinii: Evidence for the Involvement of GABAergic systems oriental Journal of chemistry, 35(4): 433-1442.
- JaffalS, Abbas M (2018) Antinociceptive action of Ononis spinosa leaf extract in mouse pain models Acta poloniae pharmaceutica, 11
- Manal A Abbas, Darwish Badran, Ahmad Disi (2018) Effect of Nordihydroguaiaretic Acid on Spermatogenesis and Fertility in Rats andrologia, in press
- Manal A. Abbas, Naghm A. Hameed, Ekbal H. Al-Khateeb and Rana M-N. Al Haj (2018) Evaluation of toxicity and fertility effects of Inula viscosa aerial parts extract in male rats Jordan Journal of Biological Sciences, accepted
- (2018) Antinociceptive effect of Achillea biebersteinii methanolic extract in BALB/c mice Neuroscience,
- Manal A Abbas (2017) Is the use of plants in Jordanian folk medicine for the treatment of male sexual dysfunction scientifically based? Review of in vitro and in vivo human and animal studies andrologia, 49(3)
- Tikriti A, Al Khatib, E, Abbas MA (2017) Teucrium polium hexane extract downregulated androgen receptor in testis and decreased fertility index in rats Human and Experimental Toxicology, in press
- Manal AAbbas (2017) Physiological Functions of Vitamin D in Adipose Tissue Journal of Steroid Biochemistry and Molecular Biology, in press
- (2017) Antinociceptive effect of Ajuga chamaepitys methanolic extract in BALB/c mice Neuroscience,
- Malek A. Zihlif, Ismail S. Mahmoud, Majd T. Ghanim, Manar S. Zreikat, Nasr Alrabadi, Amer Imraish, Fadwa Odeh, Manal A. Abbas, and Said I. Ismail (2015) Thymoquinone efficiently inhibits the survival of EBV infected B cells and alters EBV gene expression. Integr Cancer Ther, 12(3):257-63
- (2015) Nordihydroguaiaretic Acid (Masoprocol) Induces Apoptosis In Endometrial Implants In A Rat-surgical Model The 1st Endometriosis Conference of the Jordanian Society of Obstetricians and Gynecologists & the 4th Asian Congress on Endometriosis,
- Manal A.Abbas, MutasemO.Taha, AhmadM.Disi, MahaShomaf (2013) Regression of Endometrial Implants treated with vitamin D3 in a Rat Model of Endometriosis European Journal of obstetrics & gynecology & reproductive biology, 715(1-3):72-75
- Abbas, M.A., Disi, A.M. Taha, M. O. (2013) Sunitinib as an Anti-Endometriotic Agent. European Journal of Pharmaceutical Sciences, 715(1-3):72-75
- Manal A.Abbas, MutasemO.Taha, MalekA.Zihlif, AhmadM.Disi (2013) β-Caryophyllene Causes Regression of Endometrial Implants in a Rat Model of Endometriosis without Affecting Fertility European Journal of Pharmacology, 702: 12-19
- Manal Abbas, Ahmad Disi, Suleiman Al-Khalil (2009) Isolation and Identification of Anti-Ulcer Components from Anchusa strigosa Root. Jordan Journal of Pharmaceutical Sciences., l 2 (2) 131-139
- (1997) anti ulcer action of Anchusa strigosa The 8th Arab conference on biological sciences,
CONFERENCES AND WORKSHOPS
| Conference Title | Type of Participation | Location | Date |
|---|---|---|---|
| (IPCPHS) | Participate in the organization of Conference | Malaysia | January / 2022 |
| Neuroscience | Paper/Poster | Washington, DC | November / 2018 |
| Neuroscience | Paper/Poster | Washington, DC | November / 2017 |
| The 1st Endometriosis Conference of the Jordanian Society of Obstetricians and Gynecologists & the 4th Asian Congress on Endometriosis | Paper/Poster | Dead Sea | November / 2015 |
| The 8th Arab conference on biological sciences | Paper/Poster AND Participate in the organization of Conference | Amman Jordan | February / 1997 |
THESIS SUPERVISION
| Title | Location | Date |
|---|---|---|
| Association of Factor V Leiden, Factor II, and MTHFR mutations with early recurrent abortion in Jordan. | Al-Ahliyya Amman University | 2024 |
| Prevalence of CD200 and CD56 Markers Expression in Acute Leukemia Patients: A Cross-sectional Study | Al-Ahliyya Amman University | 2024 |
| Effect of Palbociclib on expression of platelets activation marker "CD62P" after co culture with breast cancer cells | Al-Ahliyya Amman University | 2023 |
| Effect of Entinostat and Genistein combination on colorectal cancer-induced by AOM/DSS mouse model. | Al-Ahliyya Amman University | 2023 |
| Diagnosis of Disseminated Intravascular Coagulation in Children with Acute Leukemia. | Al-Ahliyya Amman University | 2023 |
| Anticancer Effect of Entinostat and Genistein Combination on Colorectal cancer cell lines | Al-Ahliyya Amman University | 2023 |
| The effect of Rhoifolin and Doxorubicin combination on MDA-MB-231 triple negative breast cancer. | Al-Ahliyya Amman University | 2023 |
| The Effect of Diosmin and Cisplatin Co-Treatment on MDA-MB-231 triple negative breast cancer cell line. | Al-Ahliyya Amman University | 2023 |
| miR-192-5p as potential biomarker for chronic kidney disease in Jordan | Al-Ahliyya Amman University | 2022 |
| Correlation between uric acid level and insulin resistance in patients with polycystic ovary syndrome | Al-Ahliyya Amman University | 2022 |
| Expression of Programmed Death-Ligand 1 Protein in Head and Neck Squamous Cell Carcinoma and its Clinicopathological correlates | Al-Ahliyya Amman University | 2021 |
| Effect of Ribociclib treatment on platelet aggregation in hormone positive, HER2 negative metastatic breast cancer | Al-Ahliyya Amman University | 2020 |
| Effect of Teucrium polium extracts on male reproductive system | Al-Ahliyya Amman University | 2015 |
AWARDS AND SCHOLARSHIP
| Title | Location | Date |
|---|---|---|
| none | 1965 | |
| none | 1965 |
